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Fosfomycin for Injection (ZTI-01) Versus Piperacillin-tazobactam for the Treatment of Complicated Urinary Tract Infection Including Acute Pyelonephritis: ZEUS, A Phase 2/3 Randomized Trial
BACKGROUND: ZTI-01 (fosfomycin for injection) is an epoxide antibiotic with a differentiated mechanism of action (MOA) inhibiting an early step in bacterial cell wall synthesis. ZTI-01 has broad in vitro spectrum of activity, including multidrug-resistant Gram-negative pathogens, and is being develo...
Autores principales: | Kaye, Keith S, Rice, Louis B, Dane, Aaron L, Stus, Viktor, Sagan, Olexiy, Fedosiuk, Elena, Das, Anita F, Skarinsky, David, Eckburg, Paul B, Ellis-Grosse, Evelyn J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6880332/ https://www.ncbi.nlm.nih.gov/pubmed/30861061 http://dx.doi.org/10.1093/cid/ciz181 |
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