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Building an Otoscopic screening prototype tool using deep learning

BACKGROUND: Otologic diseases are often difficult to diagnose accurately for primary care providers. Deep learning methods have been applied with great success in many areas of medicine, often outperforming well trained human observers. The aim of this work was to develop and evaluate an automatic s...

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Autores principales: Livingstone, Devon, Talai, Aron S., Chau, Justin, Forkert, Nils D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6880418/
https://www.ncbi.nlm.nih.gov/pubmed/31771647
http://dx.doi.org/10.1186/s40463-019-0389-9
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author Livingstone, Devon
Talai, Aron S.
Chau, Justin
Forkert, Nils D.
author_facet Livingstone, Devon
Talai, Aron S.
Chau, Justin
Forkert, Nils D.
author_sort Livingstone, Devon
collection PubMed
description BACKGROUND: Otologic diseases are often difficult to diagnose accurately for primary care providers. Deep learning methods have been applied with great success in many areas of medicine, often outperforming well trained human observers. The aim of this work was to develop and evaluate an automatic software prototype to identify otologic abnormalities using a deep convolutional neural network. MATERIAL AND METHODS: A database of 734 unique otoscopic images of various ear pathologies, including 63 cerumen impactions, 120 tympanostomy tubes, and 346 normal tympanic membranes were acquired. 80% of the images were used for the training of a convolutional neural network and the remaining 20% were used for algorithm validation. Image augmentation was employed on the training dataset to increase the number of training images. The general network architecture consisted of three convolutional layers plus batch normalization and dropout layers to avoid over fitting. RESULTS: The validation based on 45 datasets not used for model training revealed that the proposed deep convolutional neural network is capable of identifying and differentiating between normal tympanic membranes, tympanostomy tubes, and cerumen impactions with an overall accuracy of 84.4%. CONCLUSION: Our study shows that deep convolutional neural networks hold immense potential as a diagnostic adjunct for otologic disease management.
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spelling pubmed-68804182019-11-29 Building an Otoscopic screening prototype tool using deep learning Livingstone, Devon Talai, Aron S. Chau, Justin Forkert, Nils D. J Otolaryngol Head Neck Surg Original Research Article BACKGROUND: Otologic diseases are often difficult to diagnose accurately for primary care providers. Deep learning methods have been applied with great success in many areas of medicine, often outperforming well trained human observers. The aim of this work was to develop and evaluate an automatic software prototype to identify otologic abnormalities using a deep convolutional neural network. MATERIAL AND METHODS: A database of 734 unique otoscopic images of various ear pathologies, including 63 cerumen impactions, 120 tympanostomy tubes, and 346 normal tympanic membranes were acquired. 80% of the images were used for the training of a convolutional neural network and the remaining 20% were used for algorithm validation. Image augmentation was employed on the training dataset to increase the number of training images. The general network architecture consisted of three convolutional layers plus batch normalization and dropout layers to avoid over fitting. RESULTS: The validation based on 45 datasets not used for model training revealed that the proposed deep convolutional neural network is capable of identifying and differentiating between normal tympanic membranes, tympanostomy tubes, and cerumen impactions with an overall accuracy of 84.4%. CONCLUSION: Our study shows that deep convolutional neural networks hold immense potential as a diagnostic adjunct for otologic disease management. BioMed Central 2019-11-26 /pmc/articles/PMC6880418/ /pubmed/31771647 http://dx.doi.org/10.1186/s40463-019-0389-9 Text en © The Author(s). 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Original Research Article
Livingstone, Devon
Talai, Aron S.
Chau, Justin
Forkert, Nils D.
Building an Otoscopic screening prototype tool using deep learning
title Building an Otoscopic screening prototype tool using deep learning
title_full Building an Otoscopic screening prototype tool using deep learning
title_fullStr Building an Otoscopic screening prototype tool using deep learning
title_full_unstemmed Building an Otoscopic screening prototype tool using deep learning
title_short Building an Otoscopic screening prototype tool using deep learning
title_sort building an otoscopic screening prototype tool using deep learning
topic Original Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6880418/
https://www.ncbi.nlm.nih.gov/pubmed/31771647
http://dx.doi.org/10.1186/s40463-019-0389-9
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