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Accumulation of damaged mitochondria in alveolar macrophages with reduced OXPHOS related gene expression in IPF
BACKGROUND: Impaired mitochondria homeostasis and function are established hallmarks of aging and increasing evidence suggests a link with lung fibrosis. Mitochondria homeostasis may be also affected in alveolar macrophages (AMs) in idiopathic pulmonary fibrosis (IPF). In this study, we used broncho...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6880424/ https://www.ncbi.nlm.nih.gov/pubmed/31775876 http://dx.doi.org/10.1186/s12931-019-1196-6 |