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Flow-enhanced priming of hESCs through H2B acetylation and chromatin decondensation
BACKGROUND: Distinct mechanical stimuli are known to manipulate the behaviors of embryonic stem cells (ESCs). Fundamental rationale of how ESCs respond to mechanical forces and the potential biological effects remain elusive. Here we conducted the mechanobiological study for hESCs upon mechanomics a...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6880446/ https://www.ncbi.nlm.nih.gov/pubmed/31775893 http://dx.doi.org/10.1186/s13287-019-1454-z |