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TLR9 activation cooperates with T cell checkpoint blockade to regress poorly immunogenic melanoma
Tumors that lack pre-existing immune infiltration respond poorly to T cell checkpoint blockade immunotherapy. These cancers often surround themselves with high densities of suppressive myeloid stroma while excluding immunostimulatory dendritic cells. Tumor-resident myeloid cells and selected lymphoc...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6880482/ https://www.ncbi.nlm.nih.gov/pubmed/31771649 http://dx.doi.org/10.1186/s40425-019-0811-x |