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Chemical tuning of photoswitchable azobenzenes: a photopharmacological case study using nicotinic transmission
We have developed photochromic probes for the nicotinic acetylcholine receptor that exploit the unique chemical properties of the tetrafluoroazobenzene (4FAB) scaffold. Ultraviolet light switching and rapid thermal relaxation of the metastable cis configuration are the main drawbacks associated with...
Autores principales: | Sansalone, Lorenzo, Zhao, Jun, Richers, Matthew T, Ellis-Davies, Graham C R |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Beilstein-Institut
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6880823/ https://www.ncbi.nlm.nih.gov/pubmed/31807216 http://dx.doi.org/10.3762/bjoc.15.274 |
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