Dysregulated miRNome of plasmacytoid dendritic cells from patients with Sjögren’s syndrome is associated with processes at the centre of their function

OBJECTIVE: A considerable body of evidence supports a role for type-I IFN in the pathogenesis of primary SS (pSS). As plasmacytoid dendritic cells (pDCs) are a major source of type-I IFN, we investigated their molecular regulation by measuring expression of a large set of miRNAs. METHODS: pDCs were...

Descripción completa

Detalles Bibliográficos
Autores principales: Hillen, Maarten R, Chouri, Eleni, Wang, Maojie, Blokland, Sofie L M, Hartgring, Sarita A Y, Concepcion, Arno N, Kruize, Aike A, Burgering, Boudewijn M T, Rossato, Marzia, van Roon, Joel A G, Radstake, Timothy R D J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Basic and Translational Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6880856/
https://www.ncbi.nlm.nih.gov/pubmed/31131409
http://dx.doi.org/10.1093/rheumatology/kez195

Ejemplares similares

Ejemplares similares