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SON protects nascent transcripts from unproductive degradation by counteracting DIP1

Gene expression involves the transcription and splicing of nascent transcripts through the removal of introns. In Drosophila, a double-stranded RNA binding protein Disco-interacting protein 1 (DIP1) targets INE-1 stable intronic sequence RNAs (sisRNAs) for degradation after splicing. How nascent tra...

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Detalles Bibliográficos
Autores principales: Tay, Mandy Li-Ian, Pek, Jun Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881055/
https://www.ncbi.nlm.nih.gov/pubmed/31730657
http://dx.doi.org/10.1371/journal.pgen.1008498

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