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The Role of the miR-21/SPRY2 Axis in Modulating Proangiogenic Factors, Epithelial Phenotypes, and Wound Healing in Corneal Epithelial Cells

PURPOSE: Subconjunctival injection of antagomir-21 attenuates the progression of corneal neovascularization. We examined the underlying mechanism by investigating the regulation of microRNA (miR)-21 expression and the involvement of miR-21 in the homeostasis of corneal epithelial cells. METHODS: Cor...

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Detalles Bibliográficos
Autores principales: Zhang, Yun, Yuan, Fukang, Liu, Lin, Chen, Zufeng, Ma, Xiaoyun, Lin, Zhen, Zou, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881141/
https://www.ncbi.nlm.nih.gov/pubmed/31529118
http://dx.doi.org/10.1167/iovs.19-27013