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Induction of Sertoli-like cells from human fibroblasts by NR5A1 and GATA4

Sertoli cells are essential nurse cells in the testis that regulate the process of spermatogenesis and establish the immune-privileged environment of the blood-testis-barrier (BTB). Here, we report the in vitro reprogramming of fibroblasts to human induced Sertoli-like cells (hiSCs). Initially, five...

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Detalles Bibliográficos
Autores principales:	Liang, Jianlin, Wang, Nan, He, Jing, Du, Jian, Guo, Yahui, Li, Lin, Wu, Wenbo, Yao, Chencheng, Li, Zheng, Kee, Kehkooi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2019
Materias:	Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881147/ https://www.ncbi.nlm.nih.gov/pubmed/31710289 http://dx.doi.org/10.7554/eLife.48767

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