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Phospholipid remodeling is critical for stem cell pluripotency by facilitating mesenchymal-to-epithelial transition

Metabolic reprogramming has emerged as a key regulator of cell fate decisions. Roles of glucose and amino acid metabolism have been extensively documented, whereas lipid metabolism in pluripotency remains largely unexplored. Using a high-coverage lipidomics approach, we reveal dynamic changes in pho...

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Detalles Bibliográficos
Autores principales: Wu, Yi, Chen, Keshi, Xing, Guangsuo, Li, Linpeng, Ma, Bochao, Hu, Zhijuan, Duan, Lifan, Liu, Xingguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881163/
https://www.ncbi.nlm.nih.gov/pubmed/31807705
http://dx.doi.org/10.1126/sciadv.aax7525