Massive clonal expansion of medulloblastoma-specific T cells during adoptive cellular therapy

In both human and murine systems, we have developed an adoptive cellular therapy platform against medulloblastoma and glioblastoma that uses dendritic cells pulsed with a tumor RNA transcriptome to expand polyclonal tumor-reactive T cells against a plurality of antigens within heterogeneous brain tu...

Descripción completa

Detalles Bibliográficos
Autores principales: Flores, C., Wildes, T., Dean, B. DiVita, Moore, G., Drake, J., Abraham, R., Gil, J., Yegorov, O., Yang, C., Dean, J., Moneypenny, C., Shin, D., Pham, C., Krauser, J., King, J., Grant, G., Driscoll, T., Kurtzberg, J., McLendon, R., Gururangan, S., Mitchell, D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881165/
https://www.ncbi.nlm.nih.gov/pubmed/31807694
http://dx.doi.org/10.1126/sciadv.aav9879

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881165/
https://www.ncbi.nlm.nih.gov/pubmed/31807694
http://dx.doi.org/10.1126/sciadv.aav9879

Ejemplares similares