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The FCGR2C allele that modulated the risk of HIV-1 infection in the Thai RV144 vaccine trial is implicated in HIV-1 disease progression

In the HIV-1 Thai RV144 vaccine trial—the only trial to demonstrate any vaccine efficacy to date—a three-variant haplotype within the Fc gamma receptor 2C gene (FCGR2C) modified the risk of HIV-1 acquisition. A similar vaccine regimen is currently being evaluated in South Africa in the HVTN702 trial...

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Detalles Bibliográficos
Autores principales:	Lassaunière, Ria, Paximadis, Maria, Ebrahim, Osman, Chaisson, Richard E., Martinson, Neil A., Tiemessen, Caroline T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881233/ https://www.ncbi.nlm.nih.gov/pubmed/30563969 http://dx.doi.org/10.1038/s41435-018-0053-9

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