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The RNA-Binding Protein RBM3 Promotes Neural Stem Cell (NSC) Proliferation Under Hypoxia
Neural stem cells (NSCs) reside physiologically in a hypoxic niche to maintain self-renewal and multipotency. Whereas mild hypoxia is known to promote NSC proliferation, severe hypoxia in pathological conditions exerts the reverse effect. The multi-functional RNA-binding protein RBM3 is abundant in...
Autores principales: | Yan, Jingyi, Goerne, Tessa, Zelmer, Andrea, Guzman, Raphael, Kapfhammer, Josef P., Wellmann, Sven, Zhu, Xinzhou |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881237/ https://www.ncbi.nlm.nih.gov/pubmed/31824945 http://dx.doi.org/10.3389/fcell.2019.00288 |
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