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ABCA1 transporter reduces amphotericin B cytotoxicity in mammalian cells
Amphotericin B (AmB) belongs to a group of polyene antibiotics commonly used in the treatment of systemic mycotic infections. A widely accepted mechanism of action of AmB is based on the formation of an oligomeric pore structure within the plasma membrane (PM) by interaction with membrane sterols. A...
Autores principales: | Wu, A., Grela, E., Wójtowicz, K., Filipczak, N., Hamon, Y., Luchowski, R., Grudziński, W., Raducka-Jaszul, O., Gagoś, M., Szczepaniak, A., Chimini, G., Gruszecki, W. I., Trombik, T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881254/ https://www.ncbi.nlm.nih.gov/pubmed/31134303 http://dx.doi.org/10.1007/s00018-019-03154-w |
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