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ABCA1 transporter reduces amphotericin B cytotoxicity in mammalian cells

Amphotericin B (AmB) belongs to a group of polyene antibiotics commonly used in the treatment of systemic mycotic infections. A widely accepted mechanism of action of AmB is based on the formation of an oligomeric pore structure within the plasma membrane (PM) by interaction with membrane sterols. A...

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Detalles Bibliográficos
Autores principales: Wu, A., Grela, E., Wójtowicz, K., Filipczak, N., Hamon, Y., Luchowski, R., Grudziński, W., Raducka-Jaszul, O., Gagoś, M., Szczepaniak, A., Chimini, G., Gruszecki, W. I., Trombik, T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881254/
https://www.ncbi.nlm.nih.gov/pubmed/31134303
http://dx.doi.org/10.1007/s00018-019-03154-w

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