Multi-trait genome-wide association study identifies new loci associated with optic disc parameters

A new avenue of mining published genome-wide association studies includes the joint analysis of related traits. The power of this approach depends on the genetic correlation of traits, which reflects the number of pleiotropic loci, i.e. genetic loci influencing multiple traits. Here, we applied new...

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Detalles Bibliográficos
Autores principales: Bonnemaijer, Pieter W. M., Leeuwen, Elisabeth M. van, Iglesias, Adriana I., Gharahkhani, Puya, Vitart, Veronique, Khawaja, Anthony P., Simcoe, Mark, Höhn, René, Cree, Angela J., Igo, Rob P., Gerhold-Ay, Aslihan, Nickels, Stefan, Wilson, James F., Hayward, Caroline, Boutin, Thibaud S., Polašek, Ozren, Aung, Tin, Khor, Chiea Chuen, Amin, Najaf, Lotery, Andrew J., Wiggs, Janey L., Cheng, Ching-Yu, Hysi, Pirro G., Hammond, Christopher J., Thiadens, Alberta A. H. J., MacGregor, Stuart, Klaver, Caroline C. W., Duijn, Cornelia M. van
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881308/
https://www.ncbi.nlm.nih.gov/pubmed/31798171
http://dx.doi.org/10.1038/s42003-019-0634-9

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