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Homogenous generation of dopaminergic neurons from multiple hiPSC lines by transient expression of transcription factors
A major hallmark of Parkinson's disease is loss of dopaminergic neurons in the substantia nigra pars compacta (SNpc). The pathophysiological mechanisms causing this relatively selective neurodegeneration are poorly understood, and thus experimental systems allowing to study dopaminergic neuron...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881336/ https://www.ncbi.nlm.nih.gov/pubmed/31776327 http://dx.doi.org/10.1038/s41419-019-2133-9 |