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Cromolyn sodium delays disease onset and is neuroprotective in the SOD1(G93A) Mouse Model of amyotrophic lateral sclerosis
Accumulating evidence suggests that neuroinflammatory processes are implicated in the initiation and progression of amyotrophic lateral sclerosis (ALS). Previous reports have demonstrated an increase in microgliosis and astrogliosis in the lumbar spinal cord of SOD1(G93A) transgenic mice before the...
Autores principales: | Granucci, Eric J., Griciuc, Ana, Mueller, Kaly A., Mills, Alexandra N., Le, Hoang, Dios, Amanda M., McGinty, Danielle, Pereira, Joao, Elmaleh, David, Berry, James D., Paganoni, Sabrina, Cudkowicz, Merit E., Tanzi, Rudolph E., Sadri-Vakili, Ghazaleh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881366/ https://www.ncbi.nlm.nih.gov/pubmed/31776380 http://dx.doi.org/10.1038/s41598-019-53982-w |
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