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Phosphorylation of the histone demethylase KDM5B and regulation of the phenotype of triple negative breast cancer

Epigenetic modifications are known to play critical roles in the expression of genes related to differentiation and dedifferentiation. Histone lysine demethylase KDM5B (PLU-1) catalyzes the demethylation of histone H3 on Lys 4 (H3K4), which results in the repression of gene expression. KDM5B is invo...

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Detalles Bibliográficos
Autores principales:	Yeh, I-Ju, Esakov, Emily, Lathia, Justin D., Miyagi, Masaru, Reizes, Ofer, Montano, Monica M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881367/ https://www.ncbi.nlm.nih.gov/pubmed/31776402 http://dx.doi.org/10.1038/s41598-019-54184-0

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