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Lipid order and charge protect killer T cells from accidental death
Killer T cells (cytotoxic T lymphocytes, CTLs) maintain immune homoeostasis by eliminating virus-infected and cancerous cells. CTLs achieve this by forming an immunological synapse with their targets and secreting a pore-forming protein (perforin) and pro-apoptotic serine proteases (granzymes) into...
Autores principales: | Rudd-Schmidt, Jesse A., Hodel, Adrian W., Noori, Tahereh, Lopez, Jamie A., Cho, Hyun-Jung, Verschoor, Sandra, Ciccone, Annette, Trapani, Joseph A., Hoogenboom, Bart W., Voskoboinik, Ilia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881447/ https://www.ncbi.nlm.nih.gov/pubmed/31776337 http://dx.doi.org/10.1038/s41467-019-13385-x |
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