Cargando…

CTGF Attenuates Tendon-Derived Stem/Progenitor Cell Aging

Aged tendon-derived stem/progenitor cells (TSPCs) lead to age-related tendon disorders and impair tendon healing. However, the underlying molecular mechanisms of TSPC aging remain largely unknown. Here, we investigated the role of connective tissue growth factor (CTGF) in TSPC aging. CTGF protein an...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rui, Yun-feng, Chen, Min-hao, Li, Ying-juan, Xiao, Long-fei, Geng, Peng, Wang, Pei, Xu, Zheng-yuan, Zhang, Xuan-pu, Dai, Guang-chun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881574/ https://www.ncbi.nlm.nih.gov/pubmed/31827530 http://dx.doi.org/10.1155/2019/6257537

Ejemplares similares

Tendon stem/progenitor cell ageing: Modulation and rejuvenation
por: Dai, Guang-Chun, et al.
Publicado: (2019)

Advanced glycation end productions and tendon stem/progenitor cells in pathogenesis of diabetic tendinopathy
por: Shi, Liu, et al.
Publicado: (2021)

The effect of adipose-derived stem cell sheets and CTGF on early flexor tendon healing in a canine model
por: Shen, Hua, et al.
Publicado: (2018)

AQP1 modulates tendon stem/progenitor cells senescence during tendon aging
por: Chen, Minhao, et al.
Publicado: (2020)

Fibrochondrogenic differentiation potential of tendon-derived stem/progenitor cells from human patellar tendon
por: Qin, Shengnan, et al.
Publicado: (2019)

Impaired function of tendon-derived stem cells in experimental diabetes mellitus rat tendons: implications for cellular mechanism of diabetic tendon disorder
por: SHI, Liu, et al.
Publicado: (2019)

Tendon Stem/Progenitor Cell Subpopulations and Their Implications in Tendon Biology
por: Huang, Zizhan, et al.
Publicado: (2021)

The Functions and Mechanisms of Tendon Stem/Progenitor Cells in Tendon Healing
por: Lu, Jingwei, et al.
Publicado: (2023)

Higher BMP Expression in Tendon Stem/Progenitor Cells Contributes to the Increased Heterotopic Ossification in Achilles Tendon With Aging
por: Dai, Guangchun, et al.
Publicado: (2020)

Therapeutic Roles of Tendon Stem/Progenitor Cells in Tendinopathy
por: Zhang, Xin, et al.
Publicado: (2016)

The effects of high glucose on tendon-derived stem cells: implications of the pathogenesis of diabetic tendon disorders
por: Lin, Yu-Cheng, et al.
Publicado: (2017)

Enhanced Effect of Tendon Stem/Progenitor Cells Combined With Tendon-Derived Decellularized Extracellular Matrix on Tendon Regeneration
por: Song, Haixin, et al.
Publicado: (2018)

PEDF-derived peptide promotes tendon regeneration through its mitogenic effect on tendon stem/progenitor cells
por: Ho, Tsung-Chuan, et al.
Publicado: (2019)

Inhibition of JAK-STAT Signaling Pathway Alleviates Age-Related Phenotypes in Tendon Stem/Progenitor Cells
por: Chen, Minhao, et al.
Publicado: (2021)

Noncanonical Wnt5a signaling regulates tendon stem/progenitor cells senescence
por: Chen, Minhao, et al.
Publicado: (2021)

Uncovering the cellular and molecular changes in tendon stem/progenitor cells attributed to tendon aging and degeneration
por: Kohler, Julia, et al.
Publicado: (2013)

Correlation of CTGF gene promoter methylation with CTGF expression in type 2 diabetes mellitus with or without nephropathy
por: ZHANG, HAO, et al.
Publicado: (2014)

miR-30a attenuates cardiac fibrosis in rats with myocardial infarction by inhibiting CTGF
por: Chen, Liwen, et al.
Publicado: (2018)

Radiation-induced pulmonary gene expression changes are attenuated by the CTGF antibody Pamrevlumab
por: Sternlicht, Mark D., et al.
Publicado: (2018)

Tendon-Derived Stem Cell Differentiation in the Degenerative Tendon Microenvironment
por: Liu, Chang, et al.
Publicado: (2018)

Irisin promotes the proliferation and tenogenic differentiation of rat tendon-derived stem/progenitor cells via activating YAP/TAZ
por: Xu, Langhai, et al.
Publicado: (2022)

CTGF in kidney fibrosis and glomerulonephritis
por: Toda, Naohiro, et al.
Publicado: (2018)

Tendon-Derived Progenitor Cells With Multilineage Potential Are Present Within Human Patellar Tendon
por: Leonardi, Erika A., et al.
Publicado: (2021)

MiR-375 attenuates injury of cerebral ischemia/reperfusion via targetting Ctgf
por: Ou, Jianying, et al.
Publicado: (2017)

AML-derived mesenchymal stem cells upregulate CTGF expression through the BMP pathway and induce K562-ADM fusiform transformation and chemoresistance
por: Li, Haiying, et al.
Publicado: (2019)

Selectively activated PRP exerts differential effects on tendon stem/progenitor cells and tendon healing
por: Zhang, Jianying, et al.
Publicado: (2019)

Fos Promotes Early Stage Teno‐Lineage Differentiation of Tendon Stem/Progenitor Cells in Tendon
por: Chen, Jialin, et al.
Publicado: (2017)

Prim-O-glucosylcimifugin ameliorates aging-impaired endogenous tendon regeneration by rejuvenating senescent tendon stem/progenitor cells
por: Wang, Yu, et al.
Publicado: (2023)

The CTGF -945GC polymorphism is not associated with plasma CTGF and does not predict nephropathy or outcome in type 1 diabetes
por: Dendooven, Amélie, et al.
Publicado: (2011)

STROBE: The correlation of Cyr61, CTGF, and VEGF with polymyositis/dermatomyositis
por: Chai, Ke-Xia, et al.
Publicado: (2018)

Tendon Stem/Progenitor Cells and Their Interactions with Extracellular Matrix and Mechanical Loading
por: Zhang, Chuanxin, et al.
Publicado: (2019)

Members of the Cyr61/CTGF/NOV Protein Family: Emerging Players in Hepatic Progenitor Cell Activation and Intrahepatic Cholangiocarcinoma
por: Wu, Qunfeng, et al.
Publicado: (2016)

MicroRNA-26b attenuates monocrotaline-induced pulmonary vascular remodeling via targeting connective tissue growth factor (CTGF) and cyclin D1 (CCND1)
por: Wang, Ran, et al.
Publicado: (2016)

Asymptomatic Hyperuricemia Is Associated with Achilles Tendon Rupture through Disrupting the Normal Functions of Tendon Stem/Progenitor Cells
por: Liang, Jingjing, et al.
Publicado: (2022)

Transcriptional co-activator TAZ sustains proliferation and tumorigenicity of neuroblastoma by targeting CTGF and PDGF-β
por: Wang, Mei, et al.
Publicado: (2015)

CTGF Contributes to the Development of Posterior Capsule Opacification: an in vitro and in vivo study
por: Ma, Bo, et al.
Publicado: (2018)

Mohawk impedes angiofibrosis by preventing the differentiation of tendon stem/progenitor cells into myofibroblasts
por: Mechakra, Asma, et al.
Publicado: (2022)

Single-cell analysis reveals a nestin(+) tendon stem/progenitor cell population with strong tenogenic potentiality
por: Yin, Zi, et al.
Publicado: (2016)

Aged Tendon Stem/Progenitor Cells Are Less Competent to Form 3D Tendon Organoids Due to Cell Autonomous and Matrix Production Deficits
por: Yan, Zexing, et al.
Publicado: (2020)

Comparative analysis of mesenchymal stem cell and embryonic tendon progenitor cell response to embryonic tendon biochemical and mechanical factors
por: Brown, Jeffrey P, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_ka10vvnl3or3n0nio26otf1aqh