Long Noncoding RNA lnc-HC Regulates PPARγ-Mediated Hepatic Lipid Metabolism through miR-130b-3p

Nonalcoholic fatty liver disease (NAFLD) is due to the excessive lipid accumulation within hepatocytes. Metabolic nuclear receptors (MNRs) play great roles in lipid homeostasis. We have identified a novel long noncoding RNA (lncRNA), lnc-HC, which regulates hepatocytic cholesterol metabolism through...

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Detalles Bibliográficos
Autores principales: Lan, Xi, Wu, Litao, Wu, Nan, Chen, Qian, Li, Yue, Du, Xiaojuan, Wei, Chenxi, Feng, Lina, Li, Yazhao, Osoro, Ezra Kombo, Sun, Mengyao, Ning, Qilan, Yan, Xiaofei, Yang, Xudong, Li, Dongmin, Lu, Shemin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881655/
https://www.ncbi.nlm.nih.gov/pubmed/31770672
http://dx.doi.org/10.1016/j.omtn.2019.10.018

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