Cargando…

Propofol Attenuates Hypoxia/Reoxygenation-Induced Apoptosis and Autophagy in HK-2 Cells by Inhibiting JNK Activation

PURPOSE: The aim of this study was to investigate whether propofol could attenuate hypoxia/reoxygenation-induced apoptosis and autophagy in human renal proximal tubular cells (HK-2) by inhibiting JNK activation. MATERIALS AND METHODS: HK-2 cells were treated with or without propofol or JNK inhibitor...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Huaxin, Peng, Xuan, Huang, Yayi, Xiao, Yeda, Wang, Zhuo, Zhan, Liying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Yonsei University College of Medicine 2019
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881709/ https://www.ncbi.nlm.nih.gov/pubmed/31769251 http://dx.doi.org/10.3349/ymj.2019.60.12.1195

Ejemplares similares

Inhibition of IRE1/JNK pathway in HK‐2 cells subjected to hypoxia‐reoxygenation attenuates mesangial cells‐derived extracellular matrix production
por: Liang, Yan, et al.
Publicado: (2020)

Baicalin attenuates liver hypoxia/reoxygenation injury by inducing autophagy
por: Liu, Feng, et al.
Publicado: (2018)

Propofol Suppressed Hypoxia/Reoxygenation-Induced Apoptosis in HBVSMC by Regulation of the Expression of Bcl-2, Bax, Caspase3, Kir6.1, and p-JNK
por: Zhang, Jianhai, et al.
Publicado: (2016)

Hypoxia/reoxygenation activates the JNK pathway and accelerates synovial senescence
por: Zhang, Yubiao, et al.
Publicado: (2020)

IL-33 Attenuates Anoxia/Reoxygenation-Induced Cardiomyocyte Apoptosis by Inhibition of PKCβ/JNK Pathway
por: Rui, Tao, et al.
Publicado: (2013)

Inhibition of Caveolae Contributes to Propofol Preconditioning-Suppressed Microvesicles Release and Cell Injury by Hypoxia-Reoxygenation
por: Deng, Fan, et al.
Publicado: (2017)

Pigment Epithelium-Derived Factor Mediates Autophagy and Apoptosis in Myocardial Hypoxia/Reoxygenation Injury
por: Kuo, Hsuan-Fu, et al.
Publicado: (2016)

Differential MicroRNA Profiling in a Cellular Hypoxia Reoxygenation Model upon Posthypoxic Propofol Treatment Reveals Alterations in Autophagy Signaling Network
por: Chen, Zhuo, et al.
Publicado: (2013)

Hypoxia-reoxygenation treatment attenuates gestational diabetes mellitus
por: Hou, Xiuzhen, et al.
Publicado: (2020)

Propofol and α2-Agonists Attenuate Microglia Activation and Restore Mitochondrial Function in an In Vitro Model of Microglia Hypoxia/Reoxygenation
por: Longhitano, Lucia, et al.
Publicado: (2022)

The Mechanisms of the Herbal Components of CRSAS on HK-2 Cells in a Hypoxia/Reoxygenation Model Based on Network Pharmacology
por: Ye, Naijing, et al.
Publicado: (2020)

Propofol postconditioning ameliorates hypoxia/reoxygenation induced H9c2 cell apoptosis and autophagy via upregulating forkhead transcription factors under hyperglycemia
por: Han, Rong-Hui, et al.
Publicado: (2021)

MicroRNA-92a Inhibition Attenuates Hypoxia/Reoxygenation-Induced Myocardiocyte Apoptosis by Targeting Smad7
por: Zhang, Busheng, et al.
Publicado: (2014)

Paeoniflorin alleviates hypoxia/reoxygenation injury in HK-2 cells by inhibiting apoptosis and repressing oxidative damage via Keap1/Nrf2/HO-1 pathway
por: Xing, Di, et al.
Publicado: (2023)

Curcumin attenuates hypoxia/reoxygenation-induced myocardial injury
por: Wei, Wenjuan, et al.
Publicado: (2019)

Hsa-miR-494-3p attenuates gene HtrA3 transcription to increase inflammatory response in hypoxia/reoxygenation HK2 Cells
por: Gong, Qian, et al.
Publicado: (2021)

Effect of intravenous lidocaine on short-term pain after hysteroscopy: a randomized clinical trial
por: Peng, Xuan, et al.
Publicado: (2021)

JNK Signaling Pathway Suppresses LPS-Mediated Apoptosis of HK-2 Cells by Upregulating NGAL
por: Han, Mei, et al.
Publicado: (2020)

Propofol synergizes with circAPBB2 to protect against hypoxia/reoxygenation‐induced oxidative stress, inflammation, and apoptosis of human cardiomyocytes
por: Jin, Chenghao, et al.
Publicado: (2023)

Allicin attenuates myocardial apoptosis, inflammation and mitochondrial injury during hypoxia-reoxygenation: an in vitro study
por: Deng, Xinyi, et al.
Publicado: (2021)

Ginsenoside Rh1 Alleviates HK-2 Apoptosis by Inhibiting ROS and the JNK/p53 Pathways
por: Yang, Qi, et al.
Publicado: (2020)

Cox-2 Negatively Affects the Protective Role of Propofol against Hypoxia/Reoxygenation Induced Cardiomyocytes Apoptosis through Suppressing Akt Signaling
por: Ma, Kangmu, et al.
Publicado: (2019)

miR-16-5p Regulates PTPN4 and Affects Cardiomyocyte Apoptosis and Autophagy Induced by Hypoxia/Reoxygenation
por: Cao, Zheng, et al.
Publicado: (2021)

HSP70 silencing aggravates apoptosis induced by hypoxia/reoxygenation in vitro
por: Zhai, Congying, et al.
Publicado: (2019)

Knockdown of TRIM8 Protects HK-2 Cells Against Hypoxia/Reoxygenation-Induced Injury by Inhibiting Oxidative Stress-Mediated Apoptosis and Pyroptosis via PI3K/Akt Signal Pathway
por: Zhang, Bang-Hua, et al.
Publicado: (2021)

Adiponectin Protects Hypoxia/Reoxygenation-Induced Cardiomyocyte Injury by Suppressing Autophagy
por: Guo, Jia, et al.
Publicado: (2022)

Glaucocalyxin A Ameliorates Hypoxia/Reoxygenation-Induced Injury in Human Renal Proximal Tubular Epithelial Cell Line HK-2 Cells
por: Hosohata, Keiko, et al.
Publicado: (2021)

XuefuZhuyu decoction protected cardiomyocytes against hypoxia/reoxygenation injury by inhibiting autophagy
por: Shi, Xiaowen, et al.
Publicado: (2017)

Differential Effects of Concomitant Use of Vitamins C and E on Trophoblast Apoptosis and Autophagy between Normoxia and Hypoxia-Reoxygenation
por: Hung, Tai-Ho, et al.
Publicado: (2010)

Dexmedetomidine attenuates hypoxia/reoxygenation injury in primary neonatal rat cardiomyocytes
por: Peng, Ke, et al.
Publicado: (2017)

Autophagy Functions to Prevent Methylglyoxal-Induced Apoptosis in HK-2 Cells
por: Park, So-Hyun, et al.
Publicado: (2020)

Dexmedetomidine Protects Human Renal Tubular Epithelial HK-2 Cells against Hypoxia/Reoxygenation Injury by Inactivating Endoplasmic Reticulum Stress Pathway
por: Zhai, Mingyu, et al.
Publicado: (2021)

Exploratory metabolomic analysis based on UHPLC-Q-TOF-MS/MS to study hypoxia-reoxygenation energy metabolic alterations in HK-2 cells
por: Yang, Xiaoyu, et al.
Publicado: (2023)

miR-30a-5p inhibits hypoxia/reoxygenation-induced oxidative stress and apoptosis in HK-2 renal tubular epithelial cells by targeting glutamate dehydrogenase 1 (GLUD1)
por: He, Yangbiao, et al.
Publicado: (2020)

N-n-butyl haloperidol iodide protects cardiomyocytes against hypoxia/reoxygenation injury by inhibiting autophagy
por: Wang, Bin, et al.
Publicado: (2015)

Panax notoginseng saponin attenuates hypoxia/reoxygenation-induced oxidative stress in cortical neurons★
por: Yan, Chen, et al.
Publicado: (2012)

Myosin 1b Participated in the Modulation of Hypoxia/Reoxygenation-Caused H9c2 Cell Apoptosis and Autophagy
por: Xu, Jing, et al.
Publicado: (2022)

The hypoxia–reoxygenation stress in plants
por: León, José, et al.
Publicado: (2020)

Bauhinia championii Flavone Attenuates Hypoxia-Reoxygenation Induced Apoptosis in H9c2 Cardiomyocytes by Improving Mitochondrial Dysfunction
por: Liao, Ping, et al.
Publicado: (2016)

Sevoflurane postconditioning attenuates cardiomyocyte hypoxia/reoxygenation injury via restoring mitochondrial morphology
por: Yu, Jin, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_ru3894i8tshdod3g54tmto19qu