Recombinant CC16 inhibits NLRP3/caspase-1-induced pyroptosis through p38 MAPK and ERK signaling pathways in the brain of a neonatal rat model with sepsis

BACKGROUND: Sepsis is a critical disease associated with extremely high mortality. Some severe forms of sepsis can induce brain injury, thus causing behavioral and cognitive dysfunction. Pyroptosis is a type of cell death that differs from apoptosis and plays an important role in the occurrence and...

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Detalles Bibliográficos
Autores principales: Zhou, Ruixi, Yang, Xiaoyan, Li, Xihong, Qu, Yi, Huang, Qun, Sun, Xuemei, Mu, Dezhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882041/
https://www.ncbi.nlm.nih.gov/pubmed/31775794
http://dx.doi.org/10.1186/s12974-019-1651-9

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