Cargando…
A Biomechanical Evaluation of a Next-Generation Integrated and Modular ACDF Device Possessing Full-Plate, Half-Plate, and No-Profile Fixation Iterations
STUDY DESIGN: In vitro biomechanical study. OBJECTIVES: The objective of this in vitro biomechanical range-of-motion (ROM) study was to evaluate spinal segmental stability following fixation with a novel anterior cervical discectomy and fusion (ACDF) device (“novel device”) that possesses integrated...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882088/ https://www.ncbi.nlm.nih.gov/pubmed/31819848 http://dx.doi.org/10.1177/2192568219834252 |
_version_ | 1783474077375135744 |
---|---|
author | Panchal, Ripul Gandhi, Anup Ferry, Chris Farmer, Sam Hansmann, Jeremy Wanebo, John |
author_facet | Panchal, Ripul Gandhi, Anup Ferry, Chris Farmer, Sam Hansmann, Jeremy Wanebo, John |
author_sort | Panchal, Ripul |
collection | PubMed |
description | STUDY DESIGN: In vitro biomechanical study. OBJECTIVES: The objective of this in vitro biomechanical range-of-motion (ROM) study was to evaluate spinal segmental stability following fixation with a novel anterior cervical discectomy and fusion (ACDF) device (“novel device”) that possesses integrated and modular no-profile, half-plate, and full-plate fixation capabilities. METHODS: Human cadaveric (n = 18, C3-T1) specimens were divided into 3 groups (n = 6/group). Each group would receive one novel device iteration. Specimen terminal ends were potted. Each specimen was first tested in an intact state, followed by anterior discectomy (C5/C6) and iterative instrumentation. Testing order: (1) novel device (group 1, no-profile; group 2, half-plate; group 3, full-plate); (2) novel device (all groups) with lateral mass screws (LMS); (3) traditional ACDF plate + cage; (4) traditional ACDF plate + cage + LMS. A 2 N·m moment was applied in flexion/extension (FE), lateral bending (LB), and axial rotation (AR) via a kinematic testing machine. Segmental ROM was tracked and normalized to intact conditions. Comparative statistical analyses were performed. RESULTS: Key findings: (1) the novel half- and full-plate constructs provided comparable reduction in FE and LB ROM to that of traditional plated ACDF (P ≥ .05); (2) the novel full-plate construct significantly exceeded all other anterior-only constructs (P ≤ .05) in AR ROM reduction; and (3) the novel half-plate construct significantly exceeded the no-profile construct in FE (P < .05). CONCLUSIONS: The novel ACDF device may be a versatile alternative to traditional no-profile and independent plating techniques, as it provides comparable ROM reduction in all principle motion directions, across all device iterations. |
format | Online Article Text |
id | pubmed-6882088 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-68820882019-12-09 A Biomechanical Evaluation of a Next-Generation Integrated and Modular ACDF Device Possessing Full-Plate, Half-Plate, and No-Profile Fixation Iterations Panchal, Ripul Gandhi, Anup Ferry, Chris Farmer, Sam Hansmann, Jeremy Wanebo, John Global Spine J Original Articles STUDY DESIGN: In vitro biomechanical study. OBJECTIVES: The objective of this in vitro biomechanical range-of-motion (ROM) study was to evaluate spinal segmental stability following fixation with a novel anterior cervical discectomy and fusion (ACDF) device (“novel device”) that possesses integrated and modular no-profile, half-plate, and full-plate fixation capabilities. METHODS: Human cadaveric (n = 18, C3-T1) specimens were divided into 3 groups (n = 6/group). Each group would receive one novel device iteration. Specimen terminal ends were potted. Each specimen was first tested in an intact state, followed by anterior discectomy (C5/C6) and iterative instrumentation. Testing order: (1) novel device (group 1, no-profile; group 2, half-plate; group 3, full-plate); (2) novel device (all groups) with lateral mass screws (LMS); (3) traditional ACDF plate + cage; (4) traditional ACDF plate + cage + LMS. A 2 N·m moment was applied in flexion/extension (FE), lateral bending (LB), and axial rotation (AR) via a kinematic testing machine. Segmental ROM was tracked and normalized to intact conditions. Comparative statistical analyses were performed. RESULTS: Key findings: (1) the novel half- and full-plate constructs provided comparable reduction in FE and LB ROM to that of traditional plated ACDF (P ≥ .05); (2) the novel full-plate construct significantly exceeded all other anterior-only constructs (P ≤ .05) in AR ROM reduction; and (3) the novel half-plate construct significantly exceeded the no-profile construct in FE (P < .05). CONCLUSIONS: The novel ACDF device may be a versatile alternative to traditional no-profile and independent plating techniques, as it provides comparable ROM reduction in all principle motion directions, across all device iterations. SAGE Publications 2019-03-11 2019-12 /pmc/articles/PMC6882088/ /pubmed/31819848 http://dx.doi.org/10.1177/2192568219834252 Text en © The Author(s) 2019 http://creativecommons.org/licenses/by-nc-nd/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 License (http://www.creativecommons.org/licenses/by-nc-nd/4.0/) which permits non-commercial use, reproduction and distribution of the work as published without adaptation or alteration, without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Original Articles Panchal, Ripul Gandhi, Anup Ferry, Chris Farmer, Sam Hansmann, Jeremy Wanebo, John A Biomechanical Evaluation of a Next-Generation Integrated and Modular ACDF Device Possessing Full-Plate, Half-Plate, and No-Profile Fixation Iterations |
title | A Biomechanical Evaluation of a Next-Generation Integrated and Modular ACDF Device Possessing Full-Plate, Half-Plate, and No-Profile Fixation Iterations |
title_full | A Biomechanical Evaluation of a Next-Generation Integrated and Modular ACDF Device Possessing Full-Plate, Half-Plate, and No-Profile Fixation Iterations |
title_fullStr | A Biomechanical Evaluation of a Next-Generation Integrated and Modular ACDF Device Possessing Full-Plate, Half-Plate, and No-Profile Fixation Iterations |
title_full_unstemmed | A Biomechanical Evaluation of a Next-Generation Integrated and Modular ACDF Device Possessing Full-Plate, Half-Plate, and No-Profile Fixation Iterations |
title_short | A Biomechanical Evaluation of a Next-Generation Integrated and Modular ACDF Device Possessing Full-Plate, Half-Plate, and No-Profile Fixation Iterations |
title_sort | biomechanical evaluation of a next-generation integrated and modular acdf device possessing full-plate, half-plate, and no-profile fixation iterations |
topic | Original Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882088/ https://www.ncbi.nlm.nih.gov/pubmed/31819848 http://dx.doi.org/10.1177/2192568219834252 |
work_keys_str_mv | AT panchalripul abiomechanicalevaluationofanextgenerationintegratedandmodularacdfdevicepossessingfullplatehalfplateandnoprofilefixationiterations AT gandhianup abiomechanicalevaluationofanextgenerationintegratedandmodularacdfdevicepossessingfullplatehalfplateandnoprofilefixationiterations AT ferrychris abiomechanicalevaluationofanextgenerationintegratedandmodularacdfdevicepossessingfullplatehalfplateandnoprofilefixationiterations AT farmersam abiomechanicalevaluationofanextgenerationintegratedandmodularacdfdevicepossessingfullplatehalfplateandnoprofilefixationiterations AT hansmannjeremy abiomechanicalevaluationofanextgenerationintegratedandmodularacdfdevicepossessingfullplatehalfplateandnoprofilefixationiterations AT wanebojohn abiomechanicalevaluationofanextgenerationintegratedandmodularacdfdevicepossessingfullplatehalfplateandnoprofilefixationiterations AT panchalripul biomechanicalevaluationofanextgenerationintegratedandmodularacdfdevicepossessingfullplatehalfplateandnoprofilefixationiterations AT gandhianup biomechanicalevaluationofanextgenerationintegratedandmodularacdfdevicepossessingfullplatehalfplateandnoprofilefixationiterations AT ferrychris biomechanicalevaluationofanextgenerationintegratedandmodularacdfdevicepossessingfullplatehalfplateandnoprofilefixationiterations AT farmersam biomechanicalevaluationofanextgenerationintegratedandmodularacdfdevicepossessingfullplatehalfplateandnoprofilefixationiterations AT hansmannjeremy biomechanicalevaluationofanextgenerationintegratedandmodularacdfdevicepossessingfullplatehalfplateandnoprofilefixationiterations AT wanebojohn biomechanicalevaluationofanextgenerationintegratedandmodularacdfdevicepossessingfullplatehalfplateandnoprofilefixationiterations |