Cargando…

A Biomechanical Evaluation of a Next-Generation Integrated and Modular ACDF Device Possessing Full-Plate, Half-Plate, and No-Profile Fixation Iterations

STUDY DESIGN: In vitro biomechanical study. OBJECTIVES: The objective of this in vitro biomechanical range-of-motion (ROM) study was to evaluate spinal segmental stability following fixation with a novel anterior cervical discectomy and fusion (ACDF) device (“novel device”) that possesses integrated...

Descripción completa

Detalles Bibliográficos
Autores principales: Panchal, Ripul, Gandhi, Anup, Ferry, Chris, Farmer, Sam, Hansmann, Jeremy, Wanebo, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882088/
https://www.ncbi.nlm.nih.gov/pubmed/31819848
http://dx.doi.org/10.1177/2192568219834252
_version_ 1783474077375135744
author Panchal, Ripul
Gandhi, Anup
Ferry, Chris
Farmer, Sam
Hansmann, Jeremy
Wanebo, John
author_facet Panchal, Ripul
Gandhi, Anup
Ferry, Chris
Farmer, Sam
Hansmann, Jeremy
Wanebo, John
author_sort Panchal, Ripul
collection PubMed
description STUDY DESIGN: In vitro biomechanical study. OBJECTIVES: The objective of this in vitro biomechanical range-of-motion (ROM) study was to evaluate spinal segmental stability following fixation with a novel anterior cervical discectomy and fusion (ACDF) device (“novel device”) that possesses integrated and modular no-profile, half-plate, and full-plate fixation capabilities. METHODS: Human cadaveric (n = 18, C3-T1) specimens were divided into 3 groups (n = 6/group). Each group would receive one novel device iteration. Specimen terminal ends were potted. Each specimen was first tested in an intact state, followed by anterior discectomy (C5/C6) and iterative instrumentation. Testing order: (1) novel device (group 1, no-profile; group 2, half-plate; group 3, full-plate); (2) novel device (all groups) with lateral mass screws (LMS); (3) traditional ACDF plate + cage; (4) traditional ACDF plate + cage + LMS. A 2 N·m moment was applied in flexion/extension (FE), lateral bending (LB), and axial rotation (AR) via a kinematic testing machine. Segmental ROM was tracked and normalized to intact conditions. Comparative statistical analyses were performed. RESULTS: Key findings: (1) the novel half- and full-plate constructs provided comparable reduction in FE and LB ROM to that of traditional plated ACDF (P ≥ .05); (2) the novel full-plate construct significantly exceeded all other anterior-only constructs (P ≤ .05) in AR ROM reduction; and (3) the novel half-plate construct significantly exceeded the no-profile construct in FE (P < .05). CONCLUSIONS: The novel ACDF device may be a versatile alternative to traditional no-profile and independent plating techniques, as it provides comparable ROM reduction in all principle motion directions, across all device iterations.
format Online
Article
Text
id pubmed-6882088
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher SAGE Publications
record_format MEDLINE/PubMed
spelling pubmed-68820882019-12-09 A Biomechanical Evaluation of a Next-Generation Integrated and Modular ACDF Device Possessing Full-Plate, Half-Plate, and No-Profile Fixation Iterations Panchal, Ripul Gandhi, Anup Ferry, Chris Farmer, Sam Hansmann, Jeremy Wanebo, John Global Spine J Original Articles STUDY DESIGN: In vitro biomechanical study. OBJECTIVES: The objective of this in vitro biomechanical range-of-motion (ROM) study was to evaluate spinal segmental stability following fixation with a novel anterior cervical discectomy and fusion (ACDF) device (“novel device”) that possesses integrated and modular no-profile, half-plate, and full-plate fixation capabilities. METHODS: Human cadaveric (n = 18, C3-T1) specimens were divided into 3 groups (n = 6/group). Each group would receive one novel device iteration. Specimen terminal ends were potted. Each specimen was first tested in an intact state, followed by anterior discectomy (C5/C6) and iterative instrumentation. Testing order: (1) novel device (group 1, no-profile; group 2, half-plate; group 3, full-plate); (2) novel device (all groups) with lateral mass screws (LMS); (3) traditional ACDF plate + cage; (4) traditional ACDF plate + cage + LMS. A 2 N·m moment was applied in flexion/extension (FE), lateral bending (LB), and axial rotation (AR) via a kinematic testing machine. Segmental ROM was tracked and normalized to intact conditions. Comparative statistical analyses were performed. RESULTS: Key findings: (1) the novel half- and full-plate constructs provided comparable reduction in FE and LB ROM to that of traditional plated ACDF (P ≥ .05); (2) the novel full-plate construct significantly exceeded all other anterior-only constructs (P ≤ .05) in AR ROM reduction; and (3) the novel half-plate construct significantly exceeded the no-profile construct in FE (P < .05). CONCLUSIONS: The novel ACDF device may be a versatile alternative to traditional no-profile and independent plating techniques, as it provides comparable ROM reduction in all principle motion directions, across all device iterations. SAGE Publications 2019-03-11 2019-12 /pmc/articles/PMC6882088/ /pubmed/31819848 http://dx.doi.org/10.1177/2192568219834252 Text en © The Author(s) 2019 http://creativecommons.org/licenses/by-nc-nd/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 License (http://www.creativecommons.org/licenses/by-nc-nd/4.0/) which permits non-commercial use, reproduction and distribution of the work as published without adaptation or alteration, without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Original Articles
Panchal, Ripul
Gandhi, Anup
Ferry, Chris
Farmer, Sam
Hansmann, Jeremy
Wanebo, John
A Biomechanical Evaluation of a Next-Generation Integrated and Modular ACDF Device Possessing Full-Plate, Half-Plate, and No-Profile Fixation Iterations
title A Biomechanical Evaluation of a Next-Generation Integrated and Modular ACDF Device Possessing Full-Plate, Half-Plate, and No-Profile Fixation Iterations
title_full A Biomechanical Evaluation of a Next-Generation Integrated and Modular ACDF Device Possessing Full-Plate, Half-Plate, and No-Profile Fixation Iterations
title_fullStr A Biomechanical Evaluation of a Next-Generation Integrated and Modular ACDF Device Possessing Full-Plate, Half-Plate, and No-Profile Fixation Iterations
title_full_unstemmed A Biomechanical Evaluation of a Next-Generation Integrated and Modular ACDF Device Possessing Full-Plate, Half-Plate, and No-Profile Fixation Iterations
title_short A Biomechanical Evaluation of a Next-Generation Integrated and Modular ACDF Device Possessing Full-Plate, Half-Plate, and No-Profile Fixation Iterations
title_sort biomechanical evaluation of a next-generation integrated and modular acdf device possessing full-plate, half-plate, and no-profile fixation iterations
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882088/
https://www.ncbi.nlm.nih.gov/pubmed/31819848
http://dx.doi.org/10.1177/2192568219834252
work_keys_str_mv AT panchalripul abiomechanicalevaluationofanextgenerationintegratedandmodularacdfdevicepossessingfullplatehalfplateandnoprofilefixationiterations
AT gandhianup abiomechanicalevaluationofanextgenerationintegratedandmodularacdfdevicepossessingfullplatehalfplateandnoprofilefixationiterations
AT ferrychris abiomechanicalevaluationofanextgenerationintegratedandmodularacdfdevicepossessingfullplatehalfplateandnoprofilefixationiterations
AT farmersam abiomechanicalevaluationofanextgenerationintegratedandmodularacdfdevicepossessingfullplatehalfplateandnoprofilefixationiterations
AT hansmannjeremy abiomechanicalevaluationofanextgenerationintegratedandmodularacdfdevicepossessingfullplatehalfplateandnoprofilefixationiterations
AT wanebojohn abiomechanicalevaluationofanextgenerationintegratedandmodularacdfdevicepossessingfullplatehalfplateandnoprofilefixationiterations
AT panchalripul biomechanicalevaluationofanextgenerationintegratedandmodularacdfdevicepossessingfullplatehalfplateandnoprofilefixationiterations
AT gandhianup biomechanicalevaluationofanextgenerationintegratedandmodularacdfdevicepossessingfullplatehalfplateandnoprofilefixationiterations
AT ferrychris biomechanicalevaluationofanextgenerationintegratedandmodularacdfdevicepossessingfullplatehalfplateandnoprofilefixationiterations
AT farmersam biomechanicalevaluationofanextgenerationintegratedandmodularacdfdevicepossessingfullplatehalfplateandnoprofilefixationiterations
AT hansmannjeremy biomechanicalevaluationofanextgenerationintegratedandmodularacdfdevicepossessingfullplatehalfplateandnoprofilefixationiterations
AT wanebojohn biomechanicalevaluationofanextgenerationintegratedandmodularacdfdevicepossessingfullplatehalfplateandnoprofilefixationiterations