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Recent Preoperative Lumbar Epidural Steroid Injection Is an Independent Risk Factor for Incidental Durotomy During Lumbar Discectomy

STUDY DESIGN: Retrospective review. OBJECTIVE: To investigate the association between lumbar epidural steroid injection (LESI) and incidental durotomy (ID) in patients with a diagnosis of disc herniation undergoing a primary discectomy. METHODS: A Medicare patient database was queried for patients b...

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Autores principales: Labaran, Lawal A., Puvanesarajah, Varun, Rao, Sandesh S., Chen, Dennis, Shen, Francis H., Jain, Amit, Hassanzadeh, Hamid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882093/
https://www.ncbi.nlm.nih.gov/pubmed/31819845
http://dx.doi.org/10.1177/2192568219833656
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author Labaran, Lawal A.
Puvanesarajah, Varun
Rao, Sandesh S.
Chen, Dennis
Shen, Francis H.
Jain, Amit
Hassanzadeh, Hamid
author_facet Labaran, Lawal A.
Puvanesarajah, Varun
Rao, Sandesh S.
Chen, Dennis
Shen, Francis H.
Jain, Amit
Hassanzadeh, Hamid
author_sort Labaran, Lawal A.
collection PubMed
description STUDY DESIGN: Retrospective review. OBJECTIVE: To investigate the association between lumbar epidural steroid injection (LESI) and incidental durotomy (ID) in patients with a diagnosis of disc herniation undergoing a primary discectomy. METHODS: A Medicare patient database was queried for patients between the ages of 65 and 85 years who underwent a primary lumbar discectomy for a diagnosis of lumbar disc herniation or degeneration from 2008 to 2014. Our main cohort of 64 849 patients was then divided into 2 groups: patients who experienced a dural tear (N = 2369) and our matched (age, gender, and history of diabetes) control cohort of patients who did not (N = 62 480). All patients who had a history of LESI were further identified and stratified into 4 subgroups by duration between LESI and discectomy (<3 months, 3-6 months, 6 months to 1 year, and overall), and a comparison of the relative incidence of ID was made among these subgroups. A multivariate logistic regression analysis was employed to determine the relationship between LESI and ID. RESULTS: Overall incidence of ID was 3.7%. There was a significant difference in incidence of LESI (27.1% vs 35.0%, P < .001) between our control and ID groups. An adjusted odds ratio (OR) showed that prior LESI within 3 to 6 months (OR 1.47, 95% CI 1.20-1.81, P < .001) and within less than 3 months (OR 1.46, 95% CI 1.24-1.72, P < .001) of surgery were significantly associated with ID. CONCLUSION: LESI increases the risk of ID in patients who undergo a subsequent lumbar discectomy within 6 months of injection.
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spelling pubmed-68820932019-12-09 Recent Preoperative Lumbar Epidural Steroid Injection Is an Independent Risk Factor for Incidental Durotomy During Lumbar Discectomy Labaran, Lawal A. Puvanesarajah, Varun Rao, Sandesh S. Chen, Dennis Shen, Francis H. Jain, Amit Hassanzadeh, Hamid Global Spine J Original Articles STUDY DESIGN: Retrospective review. OBJECTIVE: To investigate the association between lumbar epidural steroid injection (LESI) and incidental durotomy (ID) in patients with a diagnosis of disc herniation undergoing a primary discectomy. METHODS: A Medicare patient database was queried for patients between the ages of 65 and 85 years who underwent a primary lumbar discectomy for a diagnosis of lumbar disc herniation or degeneration from 2008 to 2014. Our main cohort of 64 849 patients was then divided into 2 groups: patients who experienced a dural tear (N = 2369) and our matched (age, gender, and history of diabetes) control cohort of patients who did not (N = 62 480). All patients who had a history of LESI were further identified and stratified into 4 subgroups by duration between LESI and discectomy (<3 months, 3-6 months, 6 months to 1 year, and overall), and a comparison of the relative incidence of ID was made among these subgroups. A multivariate logistic regression analysis was employed to determine the relationship between LESI and ID. RESULTS: Overall incidence of ID was 3.7%. There was a significant difference in incidence of LESI (27.1% vs 35.0%, P < .001) between our control and ID groups. An adjusted odds ratio (OR) showed that prior LESI within 3 to 6 months (OR 1.47, 95% CI 1.20-1.81, P < .001) and within less than 3 months (OR 1.46, 95% CI 1.24-1.72, P < .001) of surgery were significantly associated with ID. CONCLUSION: LESI increases the risk of ID in patients who undergo a subsequent lumbar discectomy within 6 months of injection. SAGE Publications 2019-03-21 2019-12 /pmc/articles/PMC6882093/ /pubmed/31819845 http://dx.doi.org/10.1177/2192568219833656 Text en © The Author(s) 2019 http://creativecommons.org/licenses/by/4.0/ This article is distributed under the terms of the Creative Commons Attribution 4.0 License (http://www.creativecommons.org/licenses/by/4.0/) which permits any use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Original Articles
Labaran, Lawal A.
Puvanesarajah, Varun
Rao, Sandesh S.
Chen, Dennis
Shen, Francis H.
Jain, Amit
Hassanzadeh, Hamid
Recent Preoperative Lumbar Epidural Steroid Injection Is an Independent Risk Factor for Incidental Durotomy During Lumbar Discectomy
title Recent Preoperative Lumbar Epidural Steroid Injection Is an Independent Risk Factor for Incidental Durotomy During Lumbar Discectomy
title_full Recent Preoperative Lumbar Epidural Steroid Injection Is an Independent Risk Factor for Incidental Durotomy During Lumbar Discectomy
title_fullStr Recent Preoperative Lumbar Epidural Steroid Injection Is an Independent Risk Factor for Incidental Durotomy During Lumbar Discectomy
title_full_unstemmed Recent Preoperative Lumbar Epidural Steroid Injection Is an Independent Risk Factor for Incidental Durotomy During Lumbar Discectomy
title_short Recent Preoperative Lumbar Epidural Steroid Injection Is an Independent Risk Factor for Incidental Durotomy During Lumbar Discectomy
title_sort recent preoperative lumbar epidural steroid injection is an independent risk factor for incidental durotomy during lumbar discectomy
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882093/
https://www.ncbi.nlm.nih.gov/pubmed/31819845
http://dx.doi.org/10.1177/2192568219833656
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