Autophagy protein NRBF2 has reduced expression in Alzheimer’s brains and modulates memory and amyloid-beta homeostasis in mice

BACKGROUND: Dysfunctional autophagy is implicated in Alzheimer’s Disease (AD) pathogenesis. The alterations in the expression of many autophagy related genes (ATGs) have been reported in AD brains; however, the disparity of the changes confounds the role of autophagy in AD. METHODS: To further under...

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Detalles Bibliográficos
Autores principales: Lachance, Véronik, Wang, Qian, Sweet, Eric, Choi, Insup, Cai, Cui-Zan, Zhuang, Xu-Xu, Zhang, Yuanxi, Jiang, Jessica Li, Blitzer, Robert D., Bozdagi-Gunal, Ozlem, Zhang, Bin, Lu, Jia-Hong, Yue, Zhenyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882183/
https://www.ncbi.nlm.nih.gov/pubmed/31775806
http://dx.doi.org/10.1186/s13024-019-0342-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882183/
https://www.ncbi.nlm.nih.gov/pubmed/31775806
http://dx.doi.org/10.1186/s13024-019-0342-4

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