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Tumor Necrosis Factor-alpha (TNF-α) Enhances miR-155-Mediated Endothelial Senescence by Targeting Sirtuin1 (SIRT1)

BACKGROUND: Sirtuin1 (SIRT1) participates in a wide variety of cellular processes, but the molecular mechanism remains largely unknown. miR-155 is an element of the inflammatory signaling pathway in atherosclerosis. Therefore, we tested the hypothesis that TNF-α stimulates miR-155 to target SIRT1 an...

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Detalles Bibliográficos
Autores principales:	Guo, Qianyun, Zhang, Haitong, Zhang, Bin, Zhang, Erli, Wu, Yongjian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Scientific Literature, Inc. 2019
Materias:	Lab/In Vitro Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882299/ https://www.ncbi.nlm.nih.gov/pubmed/31752013 http://dx.doi.org/10.12659/MSM.919721

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