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Empagliflozin, a sodium glucose co-transporter-2 inhibitor, alleviates atrial remodeling and improves mitochondrial function in high-fat diet/streptozotocin-induced diabetic rats
BACKGROUND: Diabetes mellitus is an important risk factor for atrial fibrillation (AF) development. Sodium–glucose co-transporter-2 (SGLT-2) inhibitors are used for the treatment of type 2 diabetes mellitus (T2DM). Their cardioprotective effects have been reported but whether they prevent AF in T2DM...
Autores principales: | Shao, Qingmiao, Meng, Lei, Lee, Sharen, Tse, Gary, Gong, Mengqi, Zhang, Zhiwei, Zhao, Jichao, Zhao, Yungang, Li, Guangping, Liu, Tong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882319/ https://www.ncbi.nlm.nih.gov/pubmed/31779619 http://dx.doi.org/10.1186/s12933-019-0964-4 |
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