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Clinical Characteristics and Adverse Events in Acute Coronary Syndrome Patients with a History of Peripheral Arterial Disease
BACKGROUND: In clinical observation, patients with acute coronary syndrome complicated with peripheral artery disease have poor prognosis, so the relationship between the diseases and clinical characteristics need to be further explored. OBJECTIVE: This study aims to investigate clinical characteris...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Sociedade Brasileira de Cardiologia - SBC
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882384/ https://www.ncbi.nlm.nih.gov/pubmed/31482945 http://dx.doi.org/10.5935/abc.20190150 |
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author | Kang, Yun-Peng Chen, Li-Ying Kang, Tie-Duo Liu, Wen-Xian |
author_facet | Kang, Yun-Peng Chen, Li-Ying Kang, Tie-Duo Liu, Wen-Xian |
author_sort | Kang, Yun-Peng |
collection | PubMed |
description | BACKGROUND: In clinical observation, patients with acute coronary syndrome complicated with peripheral artery disease have poor prognosis, so the relationship between the diseases and clinical characteristics need to be further explored. OBJECTIVE: This study aims to investigate clinical characteristics and independent risk factors for in-hospital adverse events in acute coronary syndrome patients with a history of peripheral arterial disease (PAD). METHODS: A total of 5,682 patients with acute coronary syndrome were included into this study. These patients were divided into two groups according to the presence or absence of a history of PAD: PAD group (n = 188), and non-PAD (control) group (n = 5,494). Then, the clinical characteristics and incidence of in-hospital adverse events were analyzed; p < 0.05 was considered statistically significant. RESULTS: The age of PAD patients was higher than that in the control group (65.5 ± 10.3 years vs. 58.6 ± 11 years, p < 0.001), and the proportion of PAD patients with diabetes history and stroke history was higher than that in the control group (73 [39%] vs. 1472 [26.8%], p = 0.018; 36 [19.3%] vs. 396 [7.2%], p < 0.001). The multivariate logistic regression analysis between groups based on in-hospital adverse events revealed that a history of PAD (OR = 1.791, p = 0.01), a history of diabetes (OR = 1.223, p = 0.001), and age of > 65 years old (OR = 4.670, p < 0.001) were independent risk factors for in-hospital adverse events. CONCLUSION: A history of PAD, advanced age, and a history of diabetes are independent risk factors for in-hospital adverse events in patients with acute coronary syndrome. |
format | Online Article Text |
id | pubmed-6882384 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Sociedade Brasileira de Cardiologia - SBC |
record_format | MEDLINE/PubMed |
spelling | pubmed-68823842019-12-03 Clinical Characteristics and Adverse Events in Acute Coronary Syndrome Patients with a History of Peripheral Arterial Disease Kang, Yun-Peng Chen, Li-Ying Kang, Tie-Duo Liu, Wen-Xian Arq Bras Cardiol Original Article BACKGROUND: In clinical observation, patients with acute coronary syndrome complicated with peripheral artery disease have poor prognosis, so the relationship between the diseases and clinical characteristics need to be further explored. OBJECTIVE: This study aims to investigate clinical characteristics and independent risk factors for in-hospital adverse events in acute coronary syndrome patients with a history of peripheral arterial disease (PAD). METHODS: A total of 5,682 patients with acute coronary syndrome were included into this study. These patients were divided into two groups according to the presence or absence of a history of PAD: PAD group (n = 188), and non-PAD (control) group (n = 5,494). Then, the clinical characteristics and incidence of in-hospital adverse events were analyzed; p < 0.05 was considered statistically significant. RESULTS: The age of PAD patients was higher than that in the control group (65.5 ± 10.3 years vs. 58.6 ± 11 years, p < 0.001), and the proportion of PAD patients with diabetes history and stroke history was higher than that in the control group (73 [39%] vs. 1472 [26.8%], p = 0.018; 36 [19.3%] vs. 396 [7.2%], p < 0.001). The multivariate logistic regression analysis between groups based on in-hospital adverse events revealed that a history of PAD (OR = 1.791, p = 0.01), a history of diabetes (OR = 1.223, p = 0.001), and age of > 65 years old (OR = 4.670, p < 0.001) were independent risk factors for in-hospital adverse events. CONCLUSION: A history of PAD, advanced age, and a history of diabetes are independent risk factors for in-hospital adverse events in patients with acute coronary syndrome. Sociedade Brasileira de Cardiologia - SBC 2019-09 /pmc/articles/PMC6882384/ /pubmed/31482945 http://dx.doi.org/10.5935/abc.20190150 Text en http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Kang, Yun-Peng Chen, Li-Ying Kang, Tie-Duo Liu, Wen-Xian Clinical Characteristics and Adverse Events in Acute Coronary Syndrome Patients with a History of Peripheral Arterial Disease |
title | Clinical Characteristics and Adverse Events in Acute Coronary
Syndrome Patients with a History of Peripheral Arterial Disease |
title_full | Clinical Characteristics and Adverse Events in Acute Coronary
Syndrome Patients with a History of Peripheral Arterial Disease |
title_fullStr | Clinical Characteristics and Adverse Events in Acute Coronary
Syndrome Patients with a History of Peripheral Arterial Disease |
title_full_unstemmed | Clinical Characteristics and Adverse Events in Acute Coronary
Syndrome Patients with a History of Peripheral Arterial Disease |
title_short | Clinical Characteristics and Adverse Events in Acute Coronary
Syndrome Patients with a History of Peripheral Arterial Disease |
title_sort | clinical characteristics and adverse events in acute coronary
syndrome patients with a history of peripheral arterial disease |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882384/ https://www.ncbi.nlm.nih.gov/pubmed/31482945 http://dx.doi.org/10.5935/abc.20190150 |
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