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Rheumatic Fever: A Disease without Color

BACKGROUND: Brazil has approximately 30.000 cases of Acute Rheumatic Fever (ARF) annually. A third of cardiovascular surgeries performed in the country are due to the sequelae of rheumatic heart disease (RHD), which is an important public health problem. OBJECTIVES: to analyze the historical series...

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Autores principales: de Figueiredo, Estevão Tavares, Azevedo, Luciana, Rezende, Marcelo Lacerda, Alves, Cristina Garcia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Cardiologia - SBC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882402/
https://www.ncbi.nlm.nih.gov/pubmed/31365604
http://dx.doi.org/10.5935/abc.20190141
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author de Figueiredo, Estevão Tavares
Azevedo, Luciana
Rezende, Marcelo Lacerda
Alves, Cristina Garcia
author_facet de Figueiredo, Estevão Tavares
Azevedo, Luciana
Rezende, Marcelo Lacerda
Alves, Cristina Garcia
author_sort de Figueiredo, Estevão Tavares
collection PubMed
description BACKGROUND: Brazil has approximately 30.000 cases of Acute Rheumatic Fever (ARF) annually. A third of cardiovascular surgeries performed in the country are due to the sequelae of rheumatic heart disease (RHD), which is an important public health problem. OBJECTIVES: to analyze the historical series of mortality rates and disease costs, projecting future trends to offer new data that may justify the need to implement a public health program for RF. METHODS: we performed a cross-sectional study with a time series analysis based on data from the Hospital Information System of Brazil from 1998 to 2016. Simple linear regression models and Holt’s Exponential Smoothing Method were used to model the behavior of the series and to do forecasts. The results of the tests with a value of p < 0.05 were considered statistically significant. RESULTS: each year, the number of deaths due to RHD increased by an average of 16.94 units and the mortality rate from ARF increased by 215%. There was a 264% increase in hospitalization expenses for RHD and RHD mortality rates increased 42.5% (p-value < 0.05). The estimated mortality rates for ARF and RHD were, respectively, 2.68 and 8.53 for 2019. The estimated cost for RHD in 2019 was US$ 26.715.897,70. CONCLUSIONS: according to the Brazilian reality, the 1-year RHD expenses would be sufficient for secondary prophylaxis (considering a Benzatin Penicillin G dose every 3 weeks) in 22.574 people for 10 years. This study corroborates the need for public health policies aimed at RHD.
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spelling pubmed-68824022019-12-03 Rheumatic Fever: A Disease without Color de Figueiredo, Estevão Tavares Azevedo, Luciana Rezende, Marcelo Lacerda Alves, Cristina Garcia Arq Bras Cardiol Original Article BACKGROUND: Brazil has approximately 30.000 cases of Acute Rheumatic Fever (ARF) annually. A third of cardiovascular surgeries performed in the country are due to the sequelae of rheumatic heart disease (RHD), which is an important public health problem. OBJECTIVES: to analyze the historical series of mortality rates and disease costs, projecting future trends to offer new data that may justify the need to implement a public health program for RF. METHODS: we performed a cross-sectional study with a time series analysis based on data from the Hospital Information System of Brazil from 1998 to 2016. Simple linear regression models and Holt’s Exponential Smoothing Method were used to model the behavior of the series and to do forecasts. The results of the tests with a value of p < 0.05 were considered statistically significant. RESULTS: each year, the number of deaths due to RHD increased by an average of 16.94 units and the mortality rate from ARF increased by 215%. There was a 264% increase in hospitalization expenses for RHD and RHD mortality rates increased 42.5% (p-value < 0.05). The estimated mortality rates for ARF and RHD were, respectively, 2.68 and 8.53 for 2019. The estimated cost for RHD in 2019 was US$ 26.715.897,70. CONCLUSIONS: according to the Brazilian reality, the 1-year RHD expenses would be sufficient for secondary prophylaxis (considering a Benzatin Penicillin G dose every 3 weeks) in 22.574 people for 10 years. This study corroborates the need for public health policies aimed at RHD. Sociedade Brasileira de Cardiologia - SBC 2019-09 /pmc/articles/PMC6882402/ /pubmed/31365604 http://dx.doi.org/10.5935/abc.20190141 Text en http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
de Figueiredo, Estevão Tavares
Azevedo, Luciana
Rezende, Marcelo Lacerda
Alves, Cristina Garcia
Rheumatic Fever: A Disease without Color
title Rheumatic Fever: A Disease without Color
title_full Rheumatic Fever: A Disease without Color
title_fullStr Rheumatic Fever: A Disease without Color
title_full_unstemmed Rheumatic Fever: A Disease without Color
title_short Rheumatic Fever: A Disease without Color
title_sort rheumatic fever: a disease without color
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882402/
https://www.ncbi.nlm.nih.gov/pubmed/31365604
http://dx.doi.org/10.5935/abc.20190141
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