Oral delivery of lycopene-loaded microemulsion for brain-targeting: preparation, characterization, pharmacokinetic evaluation and tissue distribution

Lycopene is considered as a promising neuroprotector with multiple bioactivities, while its therapeutic use in neurological disorders is restricted due to low solubility, instability and limited bioavailability. Our work aimed to develop lycopene-loaded microemulsion (LME) and investigate its potent...

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Detalles Bibliográficos
Autores principales: Guo, Yunliang, Mao, Xuyan, Zhang, Jing, Sun, Peng, Wang, Haiyang, Zhang, Yue, Ma, Yingjuan, Xu, Song, Lv, Renjun, Liu, Xueping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882477/
https://www.ncbi.nlm.nih.gov/pubmed/31738085
http://dx.doi.org/10.1080/10717544.2019.1689312

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