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Protein quality control: from mechanism to disease: EMBO Workshop, Costa de la Calma (Mallorca), Spain, April 28 – May 03, 2019

The cellular protein quality control machinery with its central constituents of chaperones and proteases is vital to maintain protein homeostasis under physiological conditions and to protect against acute stress conditions. Imbalances in protein homeostasis also are keys to a plethora of genetic an...

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Detalles Bibliográficos
Autores principales: Kampinga, Harm H., Mayer, Matthias P., Mogk, Axel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882752/
https://www.ncbi.nlm.nih.gov/pubmed/31713048
http://dx.doi.org/10.1007/s12192-019-01040-9
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author Kampinga, Harm H.
Mayer, Matthias P.
Mogk, Axel
author_facet Kampinga, Harm H.
Mayer, Matthias P.
Mogk, Axel
author_sort Kampinga, Harm H.
collection PubMed
description The cellular protein quality control machinery with its central constituents of chaperones and proteases is vital to maintain protein homeostasis under physiological conditions and to protect against acute stress conditions. Imbalances in protein homeostasis also are keys to a plethora of genetic and acquired, often age-related, diseases as well as aging in general. At the EMBO Workshop, speakers covered all major aspects of cellular protein quality control, from basic mechanisms at the molecular, cellular, and organismal level to medical translation. In this report, the highlights of the meeting will be summarized.
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spelling pubmed-68827522019-12-12 Protein quality control: from mechanism to disease: EMBO Workshop, Costa de la Calma (Mallorca), Spain, April 28 – May 03, 2019 Kampinga, Harm H. Mayer, Matthias P. Mogk, Axel Cell Stress Chaperones Meeting Review The cellular protein quality control machinery with its central constituents of chaperones and proteases is vital to maintain protein homeostasis under physiological conditions and to protect against acute stress conditions. Imbalances in protein homeostasis also are keys to a plethora of genetic and acquired, often age-related, diseases as well as aging in general. At the EMBO Workshop, speakers covered all major aspects of cellular protein quality control, from basic mechanisms at the molecular, cellular, and organismal level to medical translation. In this report, the highlights of the meeting will be summarized. Springer Netherlands 2019-11-11 2019-11 /pmc/articles/PMC6882752/ /pubmed/31713048 http://dx.doi.org/10.1007/s12192-019-01040-9 Text en © The Author(s) 2019 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Meeting Review
Kampinga, Harm H.
Mayer, Matthias P.
Mogk, Axel
Protein quality control: from mechanism to disease: EMBO Workshop, Costa de la Calma (Mallorca), Spain, April 28 – May 03, 2019
title Protein quality control: from mechanism to disease: EMBO Workshop, Costa de la Calma (Mallorca), Spain, April 28 – May 03, 2019
title_full Protein quality control: from mechanism to disease: EMBO Workshop, Costa de la Calma (Mallorca), Spain, April 28 – May 03, 2019
title_fullStr Protein quality control: from mechanism to disease: EMBO Workshop, Costa de la Calma (Mallorca), Spain, April 28 – May 03, 2019
title_full_unstemmed Protein quality control: from mechanism to disease: EMBO Workshop, Costa de la Calma (Mallorca), Spain, April 28 – May 03, 2019
title_short Protein quality control: from mechanism to disease: EMBO Workshop, Costa de la Calma (Mallorca), Spain, April 28 – May 03, 2019
title_sort protein quality control: from mechanism to disease: embo workshop, costa de la calma (mallorca), spain, april 28 – may 03, 2019
topic Meeting Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882752/
https://www.ncbi.nlm.nih.gov/pubmed/31713048
http://dx.doi.org/10.1007/s12192-019-01040-9
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