Cargando…

Butyric acid, a gut bacteria metabolite, lowers arterial blood pressure via colon-vagus nerve signaling and GPR41/43 receptors

Butyric acid (BA) is a short-chain fatty acid (SCFA) produced by gut bacteria in the colon. We hypothesized that colon-derived BA may affect hemodynamics. Arterial blood pressure (BP) and heart rate (HR) were recorded in anesthetized, male, 14-week-old Wistar rats. A vehicle, BA, or 3-hydroxybutyrat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Onyszkiewicz, Maksymilian, Gawrys-Kopczynska, Marta, Konopelski, Piotr, Aleksandrowicz, Marta, Sawicka, Aneta, Koźniewska, Ewa, Samborowska, Emilia, Ufnal, Marcin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2019
Materias:	Integrative Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882756/ https://www.ncbi.nlm.nih.gov/pubmed/31728701 http://dx.doi.org/10.1007/s00424-019-02322-y

Ejemplares similares

Trimethylamine, a gut bacteria metabolite and air pollutant, increases blood pressure and markers of kidney damage including proteinuria and KIM-1 in rats
por: Maksymiuk, Klaudia M., et al.
Publicado: (2022)

Effect of vasopressin-induced chronic hyponatremia on the regulation of the middle cerebral artery of the rat
por: Aleksandrowicz, Marta, et al.
Publicado: (2018)

Indole-3-Propionic Acid, a Tryptophan-Derived Bacterial Metabolite, Reduces Weight Gain in Rats
por: Konopelski, Piotr, et al.
Publicado: (2019)

TMAO, a seafood-derived molecule, produces diuresis and reduces mortality in heart failure rats
por: Gawrys-Kopczynska, Marta, et al.
Publicado: (2020)

GPR41 and GPR43 in Obesity and Inflammation – Protective or Causative?
por: Ang, Zhiwei, et al.
Publicado: (2016)

Sodium Butyrate Modulates Mucosal Inflammation Injury Mediated by GPR41/43 in the Cecum of Goats Fed a High Concentration Diet
por: Chang, Guangjun, et al.
Publicado: (2019)

Seasonal expressions of GPR41 and GPR43 in the colon of the wild ground squirrels (Spermophilus dauricus)
por: Yang, Xiaoying, et al.
Publicado: (2022)

Gut Bacteria and Hydrogen Sulfide: The New Old Players in Circulatory System Homeostasis
por: Tomasova, Lenka, et al.
Publicado: (2016)

Role of the endothelial reverse mode sodium-calcium exchanger in the dilation of the rat middle cerebral artery during hypoosmotic hyponatremia
por: Klapczyńska, Katarzyna, et al.
Publicado: (2022)

Soluble Fibre Meal Challenge Reduces Airway Inflammation and Expression of GPR43 and GPR41 in Asthma
por: Halnes, Isabel, et al.
Publicado: (2017)

Enalapril Diminishes the Diabetes-Induced Changes in Intestinal Morphology, Intestinal RAS and Blood SCFA Concentration in Rats
por: Jaworska, Kinga, et al.
Publicado: (2022)

Sodium acetate regulates milk fat synthesis through the activation of GPR41/GPR43 signaling pathway
por: Qi, Yingao, et al.
Publicado: (2023)

Urinary excretion of asymmetric (ADMA) and symmetric (SDMA) dimethylarginine is positively related to nitric oxide level in tissues of normotensive and hypertensive rats
por: Szlęzak, Dominika, et al.
Publicado: (2023)

Butyrate Increases Intracellular Calcium Levels and Enhances Growth Hormone Release from Rat Anterior Pituitary Cells via the G-Protein-Coupled Receptors GPR41 and 43
por: Miletta, Maria Consolata, et al.
Publicado: (2014)

Butyrate Attenuates Hepatic Steatosis Induced by a High‐Fat and Fiber‐Deficient Diet via the Hepatic GPR41/43‐CaMKII/HDAC1‐CREB Pathway
por: Zheng, Mingxuan, et al.
Publicado: (2022)

His-Leu, an angiotensin I-derived peptide, does not affect haemodynamics in rats
por: Drapała, Adrian, et al.
Publicado: (2018)

Short-chain free fatty acid receptors FFA2/GPR43 and FFA3/GPR41 as new potential therapeutic targets
por: Ulven, Trond
Publicado: (2012)

Breast milk jaundice affects breastfeeding: From the perspective of intestinal flora and SCFAs-GPR41/43
por: Huang, Huan, et al.
Publicado: (2023)

Hypertension in rats is associated with an increased permeability of the colon to TMA, a gut bacteria metabolite
por: Jaworska, Kinga, et al.
Publicado: (2017)

Regulation of Energy Homeostasis by GPR41
por: Inoue, Daisuke, et al.
Publicado: (2014)

Heart Failure Disturbs Gut–Blood Barrier and Increases Plasma Trimethylamine, a Toxic Bacterial Metabolite
por: Drapala, Adrian, et al.
Publicado: (2020)

Butyrate limits the replication of porcine epidemic diarrhea virus in intestine epithelial cells by enhancing GPR43-mediated IFN-III production
por: He, Haiyan, et al.
Publicado: (2023)

Butyrate suppresses atherosclerotic inflammation by regulating macrophages and polarization via GPR43/HDAC-miRNAs axis in ApoE(−/−) mice
por: Ma, Huiyan, et al.
Publicado: (2023)

The Specificity and Broad Multitarget Properties of Ligands for the Free Fatty Acid Receptors FFA3/GPR41 and FFA2/GPR43 and the Related Hydroxycarboxylic Acid Receptor HCA2/GPR109A
por: Bisenieks, Egils, et al.
Publicado: (2021)

Microbial community shifts elicit inflammation in the caecal mucosa via the GPR41/43 signalling pathway during subacute ruminal acidosis
por: Chang, Guangjun, et al.
Publicado: (2019)

The SCFA Receptor GPR43 and Energy Metabolism
por: Kimura, Ikuo, et al.
Publicado: (2014)

Sodium butyrate protects against lipopolysaccharide-induced liver injury partially via the GPR43/ β-arrestin-2/NF-κB network
por: Luo, Qian-Jiang, et al.
Publicado: (2020)

Evaluation of the relationship between GPR43 and adiposity in human
por: Dewulf, Evelyne M, et al.
Publicado: (2013)

GPR43 Potentiates β-Cell Function in Obesity
por: McNelis, Joanne C., et al.
Publicado: (2015)

Plasma Trimethylamine-N-oxide following Cessation of L-carnitine Supplementation in Healthy Aged Women
por: Samulak, Joanna J., et al.
Publicado: (2019)

Overexpression of GPR41 attenuated glucose production in propionate-induced bovine hepatocytes
por: Lin, Miao, et al.
Publicado: (2022)

SCFAs Induce Mouse Neutrophil Chemotaxis through the GPR43 Receptor
por: Vinolo, Marco A. R., et al.
Publicado: (2011)

Microbial metabolite sensor GPR43 controls severity of experimental GVHD
por: Fujiwara, Hideaki, et al.
Publicado: (2018)

GPR43 regulation of mitochondrial damage to alleviate inflammatory reaction in sepsis
por: Zhang, Weiwei, et al.
Publicado: (2021)

The Anti-inflammatory Effects of Short Chain Fatty Acids on Lipopolysaccharide- or Tumor Necrosis Factor α-Stimulated Endothelial Cells via Activation of GPR41/43 and Inhibition of HDACs
por: Li, Meng, et al.
Publicado: (2018)

The propionate-GPR41 axis in infancy protects from subsequent bronchial asthma onset
por: Ito, Takashi, et al.
Publicado: (2023)

Acetate sensing by GPR43 alarms neutrophils and protects from severe sepsis
por: Schlatterer, Katja, et al.
Publicado: (2021)

GPR41 Regulates the Proliferation of BRECs via the PIK3-AKT-mTOR Pathway
por: Meng, Zitong, et al.
Publicado: (2023)

Melatonin alleviates titanium nanoparticles induced osteolysis via activation of butyrate/GPR109A signaling pathway
por: Wu, Yanglin, et al.
Publicado: (2021)

Release of ATP in the central nervous system during systemic inflammation: real-time measurement in the hypothalamus of conscious rabbits
por: Gourine, Alexander V, et al.
Publicado: (2007)

Cannot write session to /tmp/vufind_sessions/sess_3v0rov3dd4u75om0u3rpkbds1n