Study of the interactions of a novel monoclonal antibody, mAb059c, with the hPD-1 receptor

Programmed cell death 1 (PD-1) monoclonal antibodies have been approved by regulatory agencies for the treatment of various types of cancer, and the mechanism involves the restoration of T cell functions. We report herein the X-ray crystal structure of a fully human monoclonal antibody mAb059c fragm...

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Detalles Bibliográficos
Autores principales: Liu, Jingxian, Wang, Guiqun, Liu, Liu, Wu, Runjie, Wu, Yi, Fang, Cheng, Zhou, Xinhong, Jiao, Jing, Gu, Ying, Zhou, He, Xie, Zhenhui, Sun, Zhiwu, Chen, Dakai, Dai, Ken, Wang, Dongxu, Tang, Wei, Yang, Teddy Tat Chi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882818/
https://www.ncbi.nlm.nih.gov/pubmed/31780710
http://dx.doi.org/10.1038/s41598-019-54231-w

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