Germline and somatic mutations of homologous recombination-associated genes in Japanese ovarian cancer patients

We explored the frequency of germline and somatic mutations in homologous recombination (HR)-associated genes in major histological types of ovarian cancer. We performed targeted sequencing to assess germline and somatic mutations of 16 HR-associated genes and 4 mismatch repair (MMR) genes among 207...

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Detalles Bibliográficos
Autores principales: Sugino, Kentaro, Tamura, Ryo, Nakaoka, Hirofumi, Yachida, Nozomi, Yamaguchi, Manako, Mori, Yutaro, Yamawaki, Kaoru, Suda, Kazuaki, Ishiguro, Tatsuya, Adachi, Sosuke, Isobe, Masanori, Yamaguchi, Masayuki, Kashima, Katsunori, Motoyama, Teiichi, Inoue, Ituro, Yoshihara, Kosuke, Enomoto, Takayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882827/
https://www.ncbi.nlm.nih.gov/pubmed/31780705
http://dx.doi.org/10.1038/s41598-019-54116-y

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