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µ-opioid receptor-mediated downregulation of midline thalamic pathways to basal and central amygdala
Brain µ-opioid receptors (MOR) mediate reward and help coping with pain, social rejection, anxiety and depression. The dorsal midline thalamus (dMT) integrates visceral/emotional signals and biases behavior towards aversive or defensive states through projections to the amygdala. While a dense MOR e...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882837/ https://www.ncbi.nlm.nih.gov/pubmed/31780740 http://dx.doi.org/10.1038/s41598-019-54128-8 |