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Deletion of PLCγ1 in GABAergic neurons increases seizure susceptibility in aged mice
Synaptic inhibition plays a fundamental role in the information processing of neural circuits. It sculpts excitatory signals and prevents hyperexcitability of neurons. Owing to these essential functions, dysregulated synaptic inhibition causes a plethora of neurological disorders, including epilepsy...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882884/ https://www.ncbi.nlm.nih.gov/pubmed/31780806 http://dx.doi.org/10.1038/s41598-019-54477-4 |