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A Perspective on Polo-Like Kinase-1 Inhibition for the Treatment of Rhabdomyosarcomas
Rhabdomyosarcomas are the most common pediatric soft tissue sarcoma and are a major cause of death from cancer in young patients requiring new treatment options to improve outcomes. High-risk patients include those with metastatic or relapsed disease and tumors with PAX3-FOXO1 fusion genes that enco...
Autores principales: | Gatz, Susanne A., Aladowicz, Ewa, Casanova, Michela, Chisholm, Julia C., Kearns, Pamela R., Fulda, Simone, Geoerger, Birgit, Schäfer, Beat W., Shipley, Janet M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882953/ https://www.ncbi.nlm.nih.gov/pubmed/31824851 http://dx.doi.org/10.3389/fonc.2019.01271 |
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