Cargando…

Computational screening of nanoparticles coupling to Aβ40 peptides and fibrils

Blocking the formation, growth, and breaking of amyloid fibrils by synthetic nanosystems could provide a treatment of neurodegenerative diseases. With this in mind, here atomistic molecular dynamics simulations are used to screen for nanoparticles (NPs), covered with different mixtures of ligands, i...

Descripción completa

Detalles Bibliográficos
Autores principales: Sen, Soumyo, Vuković, Lela, Král, Petr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883061/
https://www.ncbi.nlm.nih.gov/pubmed/31780663
http://dx.doi.org/10.1038/s41598-019-52594-8

Ejemplares similares