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Computational screening of nanoparticles coupling to Aβ40 peptides and fibrils
Blocking the formation, growth, and breaking of amyloid fibrils by synthetic nanosystems could provide a treatment of neurodegenerative diseases. With this in mind, here atomistic molecular dynamics simulations are used to screen for nanoparticles (NPs), covered with different mixtures of ligands, i...
Autores principales: | Sen, Soumyo, Vuković, Lela, Král, Petr |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883061/ https://www.ncbi.nlm.nih.gov/pubmed/31780663 http://dx.doi.org/10.1038/s41598-019-52594-8 |
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