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Specificity and Efficiency of the Uracil DNA Glycosylase-Mediated Strand Cleavage Surveyed on Large Sequence Libraries

Uracil-DNA glycosylase (UDG) is a critical DNA repair enzyme that is well conserved and ubiquitous in nearly all life forms. UDG protects genomic information integrity by catalyzing the excision from DNA of uracil nucleobases resulting from misincorporation or spontaneous cytosine deamination. UDG-m...

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Detalles Bibliográficos
Autores principales:	Hölz, Kathrin, Pavlic, Angelina, Lietard, Jory, Somoza, Mark M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883067/ https://www.ncbi.nlm.nih.gov/pubmed/31780717 http://dx.doi.org/10.1038/s41598-019-54044-x

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