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Dissection of gene expression datasets into clinically relevant interaction signatures via high-dimensional correlation maximization

Gene expression is controlled by many simultaneous interactions, frequently measured collectively in biology and medicine by high-throughput technologies. It is a highly challenging task to infer from these data the generating effects and cooperating genes. Here, we present an unsupervised hypothesi...

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Detalles Bibliográficos
Autores principales: Grau, Michael, Lenz, Georg, Lenz, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883077/
https://www.ncbi.nlm.nih.gov/pubmed/31780653
http://dx.doi.org/10.1038/s41467-019-12713-5

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