Cargando…

An interbacterial toxin inhibits target cell growth by synthesizing (p)ppApp

Bacteria have evolved sophisticated mechanisms to inhibit the growth of competitors(1). One such mechanism involves type VI secretion systems, which bacteria can use to directly inject antibacterial toxins into neighboring cells. Many of these toxins target cell envelope integrity, but the full rang...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ahmad, Shehryar, Wang, Boyuan, Walker, Matthew D., Tran, Hiu-Ki R., Stogios, Peter J., Savchenko, Alexei, Grant, Robert A., McArthur, Andrew G., Laub, Michael T., Whitney, John C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883173/ https://www.ncbi.nlm.nih.gov/pubmed/31695193 http://dx.doi.org/10.1038/s41586-019-1735-9

Ejemplares similares

Identification of a broadly conserved family of enzymes that hydrolyze (p)ppApp
por: Ahmad, Shehryar, et al.
Publicado: (2023)

Small Alarmone Synthetase SasA Expression Leads to Concomitant Accumulation of pGpp, ppApp, and AppppA in Bacillus subtilis
por: Fung, Danny K., et al.
Publicado: (2020)

Estimates of Rel(Seq), Mesh1, and SAH(Mex) Hydrolysis of (p)ppGpp and (p)ppApp by Thin Layer Chromatography and NADP/NADH Coupled Assays
por: Potrykus, Katarzyna, et al.
Publicado: (2020)

An interbacterial DNA deaminase toxin directly mutagenizes surviving target populations
por: de Moraes, Marcos H, et al.
Publicado: (2021)

The Vibrio-Squid Symbiosis as a Model for Studying Interbacterial Competition
por: Septer, Alecia N.
Publicado: (2019)

Environmental Viscosity Modulates Interbacterial Killing during Habitat Transition
por: Speare, Lauren, et al.
Publicado: (2020)

Human gut bacteria harbor acquired interbacterial defense systems
por: Ross, Benjamin D., et al.
Publicado: (2019)

Quantification of Interbacterial Competition using Single-Cell Fluorescence Imaging
por: Smith, Stephanie, et al.
Publicado: (2021)

Role of Recipient Susceptibility Factors During Contact-Dependent Interbacterial Competition
por: Lin, Hsiao-Han, et al.
Publicado: (2020)

Interbacterial competition and anti‐predatory behaviour of environmental Vibrio cholerae strains
por: Drebes Dörr, Natália C., et al.
Publicado: (2020)

Affinity-based capture and identification of protein effectors of the growth regulator ppGpp
por: Wang, Boyuan, et al.
Publicado: (2018)

Location, Location, Location: an Antidote That Both Activates and Neutralizes a Toxin Used in Bacterial Warfare
por: Ahmad, Shehryar, et al.
Publicado: (2023)

Functional diversification despite structural congruence in the HipBST toxin-antitoxin system of Legionella pneumophila
por: Lin, Jordan D., et al.
Publicado: (2023)

Evolution of Interbacterial Antagonism in Bee Gut Microbiota Reflects Host and Symbiont Diversification
por: Steele, Margaret I., et al.
Publicado: (2021)

Discovery of coordinately regulated pathways that provide innate protection against interbacterial antagonism
por: Ting, See-Yeun, et al.
Publicado: (2022)

Structural and Molecular Basis for Resistance to Aminoglycoside Antibiotics by the Adenylyltransferase ANT(2″)-Ia
por: Cox, Georgina, et al.
Publicado: (2015)

Intercepting biological messages: Antibacterial molecules targeting nucleic acids during interbacterial conflicts
por: Hespanhol, Julia Takuno, et al.
Publicado: (2023)

The opportunistic pathogen Stenotrophomonas maltophilia utilizes a type IV secretion system for interbacterial killing
por: Bayer-Santos, Ethel, et al.
Publicado: (2019)

Interbacterial Transfer of Carbapenem Resistance and Large Antibiotic Resistance Islands by Natural Transformation in Pathogenic Acinetobacter
por: Godeux, Anne-Sophie, et al.
Publicado: (2022)

Pandemic Vibrio cholerae shuts down site-specific recombination to retain an interbacterial defence mechanism
por: Santoriello, Francis J., et al.
Publicado: (2020)

Identification of Type VI Secretion Systems Effector Proteins That Contribute to Interbacterial Competition in Salmonella Dublin
por: Amaya, Fernando A., et al.
Publicado: (2022)

The Legionella autoinducer LAI-1 is delivered by outer membrane vesicles to promote interbacterial and interkingdom signaling
por: Fan, Mingzhen, et al.
Publicado: (2023)

Mutations in Two Paraburkholderia phymatum Type VI Secretion Systems Cause Reduced Fitness in Interbacterial Competition
por: de Campos, Samanta Bolzan, et al.
Publicado: (2017)

Two Type VI Secretion DNase Effectors are Utilized for Interbacterial Competition in the Fish Pathogen Pseudomonas plecoglossicida
por: Li, Yanyan, et al.
Publicado: (2022)

Methylobacterium extorquens RSH Enzyme Synthesizes (p)ppGpp and pppApp in vitro and in vivo, and Leads to Discovery of pppApp Synthesis in Escherichia coli
por: Sobala, Michał, et al.
Publicado: (2019)

Structural and Functional Adaptation of Vancomycin Resistance VanT Serine Racemases
por: Meziane-Cherif, Djalal, et al.
Publicado: (2015)

ApmA Is a Unique Aminoglycoside Antibiotic Acetyltransferase That Inactivates Apramycin
por: Bordeleau, Emily, et al.
Publicado: (2021)

Agrobacterium tumefaciens Deploys a Superfamily of Type VI Secretion DNase Effectors as Weapons for Interbacterial Competition In Planta
por: Ma, Lay-Sun, et al.
Publicado: (2014)

Commensal and Pathogenic Bacterial-Derived Extracellular Vesicles in Host-Bacterial and Interbacterial Dialogues: Two Sides of the Same Coin
por: Tarashi, Samira, et al.
Publicado: (2022)

Cryptic Genes for Interbacterial Antagonism Distinguish Rickettsia Species Infecting Blacklegged Ticks From Other Rickettsia Pathogens
por: Verhoeve, Victoria I., et al.
Publicado: (2022)

Erratum for Godeux et al., “Interbacterial Transfer of Carbapenem Resistance and Large Antibiotic Resistance Islands by Natural Transformation in Pathogenic Acinetobacter”
por: Godeux, Anne-Sophie, et al.
Publicado: (2022)

Recipient Cell Factors Influence Interbacterial Competition Mediated by Two Distinct Burkholderia dolosa Contact-Dependent Growth Inhibition Systems
por: Elery, Zaria K., et al.
Publicado: (2022)

The activity of CouR, a MarR family transcriptional regulator, is modulated through a novel molecular mechanism
por: Otani, Hiroshi, et al.
Publicado: (2016)

The evolution of substrate discrimination in macrolide antibiotic resistance enzymes
por: Pawlowski, Andrew C., et al.
Publicado: (2018)

Ent2 Governs Morphogenesis and Virulence in Part through Regulation of the Cdc42 Signaling Cascade in the Fungal Pathogen Candida albicans
por: Lash, Emma, et al.
Publicado: (2023)

A novel strigolactone receptor antagonist provides insights into the structural inhibition, conditioning, and germination of the crop parasite Striga
por: Arellano-Saab, Amir, et al.
Publicado: (2022)

Synthesized Geopolymers Adsorb Bacterial Proteins, Toxins, and Cells
por: Popovich, John, et al.
Publicado: (2020)

The CpxR regulates type VI secretion system 2 expression and facilitates the interbacterial competition activity and virulence of avian pathogenic Escherichia coli
por: Yi, Zhengfei, et al.
Publicado: (2019)

Marine Toxins That Target Voltage-gated Sodium Channels
por: Al-Sabi, Ahmed, et al.
Publicado: (2006)

A Quorum Sensing-Regulated Type VI Secretion System Containing Multiple Nonredundant VgrG Proteins Is Required for Interbacterial Competition in Chromobacterium violaceum
por: Alves, Júlia A., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_dmkpolopjdmpsiev08db6rkdva