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Clinical significance of MLH1/MSH2 for stage II/III sporadic colorectal cancer

BACKGROUND: The development of colorectal cancer (CRC) is a complicated multistep process that involves an accumulation of mutations in tumor suppressor genes and oncogenes. In the process of DNA replication, base mismatch often occurs due to various factors leading to abnormal expression of mismatc...

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Detalles Bibliográficos
Autores principales: Wang, Shui-Ming, Jiang, Bin, Deng, Youping, Huang, Shu-Liang, Fang, Ming-Zhi, Wang, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883179/
https://www.ncbi.nlm.nih.gov/pubmed/31798786
http://dx.doi.org/10.4251/wjgo.v11.i11.1065

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