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Clinical significance of MLH1/MSH2 for stage II/III sporadic colorectal cancer
BACKGROUND: The development of colorectal cancer (CRC) is a complicated multistep process that involves an accumulation of mutations in tumor suppressor genes and oncogenes. In the process of DNA replication, base mismatch often occurs due to various factors leading to abnormal expression of mismatc...
Autores principales: | Wang, Shui-Ming, Jiang, Bin, Deng, Youping, Huang, Shu-Liang, Fang, Ming-Zhi, Wang, Yu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Baishideng Publishing Group Inc
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883179/ https://www.ncbi.nlm.nih.gov/pubmed/31798786 http://dx.doi.org/10.4251/wjgo.v11.i11.1065 |
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