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Safety and efficacy of a new micronized formulation of the ALIAmide palmitoylglucosamine in preclinical models of inflammation and osteoarthritis pain
BACKGROUND: Osteoarthritis is increasingly recognized as the result of a complex interplay between inflammation, chrondrodegeneration, and pain. Joint mast cells are considered to play a key role in orchestrating this detrimental triad. ALIAmides down-modulate mast cells and more generally hyperacti...
Autores principales: | Cordaro, Marika, Siracusa, Rosalba, Impellizzeri, Daniela, D’ Amico, Ramona, Peritore, Alessio Filippo, Crupi, Rosalia, Gugliandolo, Enrico, Fusco, Roberta, Di Paola, Rosanna, Schievano, Carlo, Cuzzocrea, Salvatore |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883534/ https://www.ncbi.nlm.nih.gov/pubmed/31779692 http://dx.doi.org/10.1186/s13075-019-2048-y |
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