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Usefulness and reliability of cell free fetal DNA screening for main trisomies in case of atypical profile on first trimester maternal serum screening

BACKGROUND: Patients with atypical values of HCG and/or PAPP-A are at higher risk of chromosomal abnormality and vascular complications of pregnancy. The performance of cfDNA in this particular population has not yet been evaluated. OBJECTIVES: The primary objective was to evaluate the usefulness an...

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Detalles Bibliográficos
Autores principales: Carrara, Julie, Vivanti, Alexandre, Jani, Jacques C., Demain, Adèle, Costa, Jean-Marc, Benachi, Alexandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883576/
https://www.ncbi.nlm.nih.gov/pubmed/31779618
http://dx.doi.org/10.1186/s12967-019-02152-7

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