The glucagon-like peptide-1 receptor agonist reduces inflammation and blood-brain barrier breakdown in an astrocyte-dependent manner in experimental stroke

BACKGROUND: Preserving the integrity of the blood-brain barrier (BBB) is beneficial to avoid further brain damage after acute ischemic stroke (AIS). Astrocytes, an important component of the BBB, promote BBB breakdown in subjects with AIS by secreting inflammatory factors. The glucagon-like peptide-...

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Detalles Bibliográficos
Autores principales: Shan, Yilong, Tan, Sha, Lin, Yinyao, Liao, Siyuan, Zhang, Bingjun, Chen, Xiaodong, Wang, Jihui, Deng, Zhezhi, Zeng, Qin, Zhang, Lei, Wang, Yuge, Hu, Xueqiang, Qiu, Wei, Peng, Lisheng, Lu, Zhengqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883580/
https://www.ncbi.nlm.nih.gov/pubmed/31779652
http://dx.doi.org/10.1186/s12974-019-1638-6

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