Cargando…

Systemic and central nervous system metabolic alterations in Alzheimer’s disease

BACKGROUND: Metabolic alterations, related to cerebral glucose metabolism, brain insulin resistance, and age-induced mitochondrial dysfunction, play an important role in Alzheimer’s disease (AD) on both the systemic and central nervous system level. To study the extent and significance of these alte...

Descripción completa

Detalles Bibliográficos
Autores principales:	van der Velpen, Vera, Teav, Tony, Gallart-Ayala, Héctor, Mehl, Florence, Konz, Ioana, Clark, Christopher, Oikonomidi, Aikaterini, Peyratout, Gwendoline, Henry, Hugues, Delorenzi, Mauro, Ivanisevic, Julijana, Popp, Julius
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883620/ https://www.ncbi.nlm.nih.gov/pubmed/31779690 http://dx.doi.org/10.1186/s13195-019-0551-7

Ejemplares similares

LC-HRMS data as a result of untargeted metabolomic profiling of human cerebrospinal fluid
por: Mehl, Florence, et al.
Publicado: (2018)

Single-Step Extraction Coupled with Targeted HILIC-MS/MS Approach for Comprehensive Analysis of Human Plasma Lipidome and Polar Metabolome
por: Medina, Jessica, et al.
Publicado: (2020)

Sex‐specific alterations in NAD+ metabolism in 3xTg Alzheimer’s disease mouse brain assessed by quantitative targeted LC‐MS
por: van der Velpen, Vera, et al.
Publicado: (2021)

Molecular insights into sex-specific metabolic alterations in Alzheimer’s mouse brain using multi-omics approach
por: Strefeler, Abigail, et al.
Publicado: (2023)

Metabolic View on Human Healthspan: A Lipidome-Wide Association Study
por: Carrard, Justin, et al.
Publicado: (2021)

Author Correction: Mechanistic insights into bacterial metabolic reprogramming from omics-integrated genome-scale models
por: Hadadi, Noushin, et al.
Publicado: (2020)

Mechanistic insights into bacterial metabolic reprogramming from omics-integrated genome-scale models
por: Hadadi, Noushin, et al.
Publicado: (2020)

Metabolic Impairment in Coronary Artery Disease: Elevated Serum Acylcarnitines Under the Spotlights
por: Gander, Joséphine, et al.
Publicado: (2021)

The fate of orally administered sialic acid: First insights from patients with N-acetylneuraminic acid synthase deficiency and control subjects
por: Tran, Christel, et al.
Publicado: (2021)

Experimental evolution of metabolism under nutrient restriction: enhanced amino acid catabolism and a key role of branched-chain amino acids
por: Cavigliasso, Fanny, et al.
Publicado: (2023)

Evolutionary adaptation to juvenile malnutrition impacts adult metabolism and impairs adult fitness in Drosophila
por: Erkosar, Berra, et al.
Publicado: (2023)

How Ceramides Orchestrate Cardiometabolic Health—An Ode to Physically Active Living
por: Carrard, Justin, et al.
Publicado: (2021)

The metabolic signature of cardiorespiratory fitness: a protocol for a systematic review and meta-analysis
por: Carrard, Justin, et al.
Publicado: (2021)

The Metabolic Signature of Cardiorespiratory Fitness: A Systematic Review
por: Carrard, Justin, et al.
Publicado: (2021)

Gut microbiota severely hampers the efficacy of NAD-lowering therapy in leukemia
por: ElMokh, Oussama, et al.
Publicado: (2022)

Molecular Profiling and Functional Analysis of Macrophage-Derived Tumor Extracellular Vesicles
por: Cianciaruso, Chiara, et al.
Publicado: (2019)

Key role of MIF-related neuroinflammation in neurodegeneration and cognitive impairment in Alzheimer’s disease
por: Nasiri, Elham, et al.
Publicado: (2020)

Inhibition of sphingolipid de novo synthesis counteracts muscular dystrophy
por: Laurila, Pirkka-Pekka, et al.
Publicado: (2022)

Systemic and central nervous system neuroinflammatory signatures of neuropsychiatric symptoms and related cognitive decline in older people
por: Clark, Christopher, et al.
Publicado: (2022)

Enrichment of extracellular vesicles from tissues of the central nervous system by PROSPR
por: Gallart-Palau, Xavier, et al.
Publicado: (2016)

Alzheimer disease pathology and the cerebrospinal fluid proteome
por: Dayon, Loïc, et al.
Publicado: (2018)

Integrative systems analysis identifies genetic and dietary modulators of bile acid homeostasis
por: Li, Hao, et al.
Publicado: (2022)

Investigating the circulating sphingolipidome response to a single high-intensity interval training session within healthy females and males in their twenties (SphingoHIIT): Protocol for a randomised controlled trial
por: Carrard, Justin, et al.
Publicado: (2023)

From Samples to Insights into Metabolism: Uncovering Biologically Relevant Information in LC-HRMS Metabolomics Data
por: Ivanisevic, Julijana, et al.
Publicado: (2019)

A combination of plasma membrane sterol biosynthesis and autophagy is required for shade-induced hypocotyl elongation
por: Ince, Yetkin Çaka, et al.
Publicado: (2022)

An integrative multi-omics approach reveals new central nervous system pathway alterations in Alzheimer’s disease
por: Clark, Christopher, et al.
Publicado: (2021)

Upon the Influence of the Nervous System on the Movements of the Iris
por: Budge, Julius
Publicado: (1853)

Upon the Influence of the Nervous System on the Movements of the Iris
por: Budge, Julius
Publicado: (1853)

PI5P4Kα supports prostate cancer metabolism and exposes a survival vulnerability during androgen receptor inhibition
por: Triscott, Joanna, et al.
Publicado: (2023)

Fever Therapy: Its Rationale in Diseases of the Nervous System
por: Wagner-Jauregg, Julius
Publicado: (1936)

Nanomaterials for Drug Delivery to the Central Nervous System
por: Teleanu, Daniel Mihai, et al.
Publicado: (2019)

Bioinformatics: The Next Frontier of Metabolomics
por: Johnson, Caroline H., et al.
Publicado: (2014)

De novo NAD(+) synthesis enhances mitochondrial function and improves health
por: Katsyuba, Elena, et al.
Publicado: (2018)

The Nervous System
Publicado: (1849)

Nervous System
por: Patton, G. F.
Publicado: (1871)

Nervous System
por: Miller, Andrew D., et al.
Publicado: (2017)

Nervous System
por: Cantile, Carlo, et al.
Publicado: (2016)

The Nervous System
por: White, Leander J.
Publicado: (1893)

Tumor-induced reshuffling of lipid composition on the ER membrane sustains macrophage survival and pro-tumorigenic activity
por: Di Conza, Giusy, et al.
Publicado: (2021)

Research on the Damage of the Central Nervous System Lymphoma to the Nervous System
por: Hernandez, Jairo, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_36jsentofdceru6olcsmdg21v5