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Validation of an epigenetic field of susceptibility to detect significant prostate cancer from non-tumor biopsies
BACKGROUND: An epigenetic field of cancer susceptibility exists for prostate cancer (PC) that gives rise to multifocal disease in the peripheral prostate. In previous work, genome-wide DNA methylation profiling identified altered regions in the normal prostate tissue of men with PC. In the current m...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883627/ https://www.ncbi.nlm.nih.gov/pubmed/31779677 http://dx.doi.org/10.1186/s13148-019-0771-5 |