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Validation of an epigenetic field of susceptibility to detect significant prostate cancer from non-tumor biopsies

BACKGROUND: An epigenetic field of cancer susceptibility exists for prostate cancer (PC) that gives rise to multifocal disease in the peripheral prostate. In previous work, genome-wide DNA methylation profiling identified altered regions in the normal prostate tissue of men with PC. In the current m...

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Detalles Bibliográficos
Autores principales: Yang, Bing, Etheridge, Tyler, McCormick, Johnathon, Schultz, Adam, Khemees, Tariq A., Damaschke, Nathan, Leverson, Glen, Woo, Kaitlin, Sonn, Geoffrey A., Klein, Eric A., Fumo, Mike, Huang, Wei, Jarrard, David F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883627/
https://www.ncbi.nlm.nih.gov/pubmed/31779677
http://dx.doi.org/10.1186/s13148-019-0771-5