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The TRIM protein Mitsugumin 53 enhances survival and therapeutic efficacy of stem cells in murine traumatic brain injury

BACKGROUND: Traumatic brain injury (TBI) is a common neurotrauma leading to brain dysfunction and death. Human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) hold promise in the treatment of TBI. However, their efficacy is modest due to low survival and differentiation under the harsh micr...

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Detalles Bibliográficos
Autores principales: Guan, Fangxia, Huang, Tuanjie, Wang, Xinxin, Xing, Qu, Gumpper, Kristyn, Li, Peng, Song, Jishi, Tan, Tao, Yang, Greta Luyuan, Zang, Xingxing, Zhang, Jiewen, Wang, Yuming, Yang, Yunlei, Liu, Yashi, Zhang, Yanting, Yang, Bo, Ma, Jianjie, Ma, Shanshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883632/
https://www.ncbi.nlm.nih.gov/pubmed/31779687
http://dx.doi.org/10.1186/s13287-019-1433-4